Skip to main content
OpenTrials
Completed

NCT Number: NCT00438165

Age 12 Follow-up of Early Preventive Intervention (Memphis)

To examine the impact of prenatal and infancy home visiting by nurses from child age 2 through 12.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Child Rearing Behavior Reproductive Behavior Risk Reduction Behavior

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

University of Rochester School of Nursing

Rochester, New York, 14642, United States

About this study

This study is a longitudinal follow-up of 679 low-income women (89% African American) and their firstborn and subsequent children who have participated in a randomized trial of prenatal and infancy home visiting by nurses in Memphis, Tennessee since 1988. The study was conducted when the first-born children completed sixth grade, at around their 12th birthday.

The current follow-up was designed to determine whether: a) nurse-visited women differ from comparison group women in their life-course outcomes (the number and spacing of subsequent pregnancies and births; the rates of marriage and cohabitation with the father of the child; their employment, career growth, economic self-sufficiency, and welfare dependence; and behavioral problems due to substance abuse; arrests for serious misdemeanors and felonies); b) children of nurse-visited women differ from comparison-children in their academic achievement, placements in special education, rates of grade retention, conduct in school, and academic achievement; c) there are lower rates of developmental disability, grade retention, placement in special education, and school disciplinary actions among subsequent children born to nurse-visited women; d) nurse-visited families have fewer government expenditures and higher taxes paid; e) the effects of the program on child outcomes are concentrated on children born to women with low psychological resources; f) the effects of the program on maternal life course and government costs are concentrated on women with high psychological resources; g) the effects of the program on children are greater in schools and neighborhoods that contain greater risks for academic and behavioral problems; h) the effect of the program on children's disruptive behavior problems is explained by the combined effects of the program on maternal life-course, qualities of parental care-giving, and children's sequential processing skills, and aggressive and violent themes, reliance on adults, and story incoherence in their responses to the McArthur Story Stem Battery at earlier assessments. Data will be derived from maternal interviews and reviews of state administrative and school records. Results from this trial will provide policy makers with an estimate of likely long-term effects of this program when it is conducted in close to real-life conditions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women <29 weeks gestation
  • No previous live births
  • At least 2 socio-demographic risk characteristics; e.g. unmarried, <12 years of education, unemployed.

Treatment and study plan

home visitation

Behavioral

Home visitation by nurses from midway through pregnancy until child age 12

Primary outcomes

  1. the number and spacing of subsequent pregnancies and births

    Time frame: When first child is 12

  2. the rates of marriage and cohabitation with the father of the child

    Time frame: When first child is 12

  3. mothers' employment, career growth, economic self-sufficiency, and welfare dependence

    Time frame: When first child is 12

  4. mothers' behavioral problems due to substance abuse

    Time frame: When first child is 12

  5. children's academic achievement, placements in special education, rates of grade retention, conduct in school, and academic achievement

    Time frame: At age 12

  6. rates of developmental disability, grade retention, placement in special education, and school disciplinary actions among subsequent children

    Time frame: At age 12

  7. mothers' arrests for serious misdemeanors and felonies

    Time frame: When first child is 12

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Official study title

Age 12 Follow-up of Early Preventive Intervention

Acronym: MemphisY12

Important dates

Study start
2003
Primary completion
2012
Study completion
2012
First posted
Feb 22, 2007
Registry last updated
Feb 19, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.