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Enrolling by Invitation

NCT Number: NCT07237932

Adenomyosis Clinical, Imaging and Histopathology

The goal of this clinical trial is to identify and compare the results of imaging studies and evaluating adenomyosis features and post hysterectomy results and their clinical relievants as well as to describe classification for adenomyosis based on one or a combination of clinical, imaging and histopathological features.

Main questions it aim to answer:

What's the relation between clinical symptoms ,maging and histopathological classification of adenomyosis? Research will identify relationships between clinical symptoms, imaging and histopathological classification of adenomyosis Participants will undergo transvaginal ultrasound, non contrast pelvic MRI, hysterectomy then histopathological examination for their uterus

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Key information

Conditions

Adenomyosis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Urogenital Diseases Uterine Diseases

Age range

35 year–55 year

Sex eligibility

Female

Study type

Observational

Primary location

Kafr elsheikh university

Kafr ash Shaykh, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age from 35 to 55 years old female No previous hormonal treatment for uterine adenomyosis within three months Women with heavy menstrual bleeding and dysmenorrhoea Women who completed their families Patient failed medical treatment and hysterectomy is the only remaining line for treatment -

Exclusion criteria

Patients not candidate for hysterectomy Positive pregnancy test Patients with contraindications for MRI such as patients with pacemakers, claustrophobia,or other implanted electronic devices Inadequate image quality due to motion artifact

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Treatment and study plan

Primary outcomes

  1. Classifications of adenomyosis

    Time frame: 12 months

    Class of adenomyosis according to imaging, histopathology and clinical outcomes

Sponsors and collaborators

Lead sponsor

Kafrelsheikh University

Other

Registry information

Official study title

Classifications of Adenomyosis and Correlation of Phenotypes in Imaging and Histopathology to Clinical Outcomes

Acronym: AM C/I/H

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 20, 2025
Registry last updated
Jul 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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