University of Kentucky
Lexington, Kentucky, 40506, United States
NCT Number: NCT06017154
Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes). The training program will comprise of integrate neuromuscular (agility, dynamic postural stability, shuffling, rapid acceleration/deceleration, plyometrics, lateral shuffle, and core stability) and cognitive (reaction time, processing speed, task switching, decision-making, and working memory) challenges.
Looking for future studies?
Notify Me18 year–25 year
Female
Interventional
Not applicable
Lexington, Kentucky, 40506, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The training will incorporate cognitive tasks which focus on reaction time, processing speed, working memory, cognitive flexibility, and inhibitory control using visual stimuli on a screen or through sensors which illuminate using LED lights. These cognitive tasks will be performed while also executing physical performance tasks that challenge static and dynamic postural stability, lateral movement, agility, and other movement patterns. The training session will last approximately 30 minutes and participants will complete up to 5 exercises
Time frame: 2 hours, pre-training session and immediately post-training session
During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The level of brain activation during the task will be captured and reported.
Time frame: 2 hours, pre-training session and immediately post-training session
The participant will complete a resting-state functional MRI scan in which they will lay still in the scanner. No task is performed during this scan. Functional connectivity (functionally related regions of the brain that are co-activated) during the scan will be captured and reported.
Time frame: 2 hours, pre-training session and immediately post-training session
During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The reaction time in milliseconds will be captured. The change in reaction time from pre to post training session will be reported.
Time frame: 2 hours, pre-training session and immediately post-training session
During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The percent of correct responses (accuracy) will be captured. The change in accuracy from pre to post training session will be reported.
Time frame: Once, pre-training
The demographic and injury history form is designed to capture: 1) information about the participant including age, height, weight, race, ethnicity, 2) information related to sports participation, and 3) information related to past injuries or medical conditions which are relevant to the study.
Time frame: Once, pre-training
The Defense Veterans Pain Rating Scale is a valid 5-item scale to assess pain magnitude and pain interference. This scale ranges from 0 to 10, 0 indicating no pain/interference and 10 indicating as bas as it could be/complete interference.
Time frame: Once, pre-training
16-item patient-reported outcome instrument that assesses physical and psychosocial status.This scale ranges from 0 to 4, 0 indicating no problem and 4 indicating severe.
Time frame: Once, pre-training
This survey asks individuals to self-report their general physical activity over the past week. This survey ranges from 0 to 10, 0 indicating sedentary and 10 indicating high physical activity.
Time frame: 35 minutes, during the training session
Heart rate will be monitored with a noninvasive heart rate monitor that will be worn by the participant around the chest at the level of the xiphoid process. Resting heart rate will be collected prior to the start intervention then monitored and recorded throughout the training session.
Time frame: 30 minutes, during the training session
Average reaction time in milliseconds will be captured during the exercises via light sensors.
Time frame: 30 minutes, during the training session
The number of misses will be captured during the exercises via light sensors. A miss is considered when they deactivate the wrong sensor or don't deactivate the sensor quickly enough.
Time frame: 30 minutes, during the training session
The number of hits will be captured during the exercises via light sensors. A hit is considered when they deactivate the correct sensor.
Time frame: 30 minutes, during the training session
The number of errors will be captured during the exercises by visual observation. An error occurs when they do not complete they exercise correctly.
Time frame: 30 minutes, during the training session
After each exercise the participant will be asked to rate their perceived exertion on a scale from 6 to 20, 6 indicating low perceived exertion and 20 indicating high perceived exertion
Time frame: 30 minutes, during the training session
After each exercise the participant will be asked to rate their perceived cognitive difficulty on a scale from 1 to 10, 1 indicating low cognitive challenge and 10 indicating high cognitive challenge
Ke'La H Porter
Other
The Acute Effects of Brain Activation and Functional Connectivity Following Motor-cognitive Training Using Functional MRI
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06996990
Athletic Injuries, Fatigue
Izmir, Turkey (Türkiye)
View Trial DetailsNCT06325228
Athletic Injuries, Healthy
Gdansk, Poland
View Trial DetailsNCT06257303
Ankle Injuries, Athletic Injuries
Istanbul, Turkey (Türkiye)
View Trial DetailsNCT05629182
Athletic Injuries, Injury;Sports
Zurich, Switzerland
View Trial Details