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OpenTrials
Completed

NCT Number: NCT07016594

Acute Cardiovascular Responses to Two Types of Exercise

The purpose of this research was to explore potential differences in acute cardiovascular responses between two conditions: 1) moderate-intensity cycle ergometer exercise; and 2) moderate-intensity cycle ergometer exercise with NMES. Young, healthy, physically active participants were recruited for this study.

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Key information

Conditions

Aerobic Exercise

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Active Living Centre/Applied Research Centre

Winnipeg, Manitoba, R3T2N2, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy
  • performing aerobic activity greater than or equal to three times per week at any intensity

Exclusion criteria

  • had lower body musculoskeletal injuries recently (within the past 6 months)
  • health conditions that may place risk to the individual such as those with respiratory issues, hypertension, chronic atrial fibrillation, valvular diseases, heart disease; or obstructive cardiomyopathy
  • if taking pharmacological drugs, performance-enhancing drugs, recreational drugs, nutritional supplements, or smoked nicotine

Treatment and study plan

Aerobic Exercise

Behavioral

Aerobic exercise was done with and without neuromuscular electrical stimulation

Primary outcomes

  1. Oxygen consumption

    Time frame: 20 minutes

    L/min

Secondary outcomes

  1. Carbon dioxide production

    Time frame: 20 minutes

    L/min

  2. Heart rate

    Time frame: 20 minutes

    bpm

  3. Respiratory exchange ratio

    Time frame: 20 minutes

    RER (0.70-1.00)

  4. Rating of perceived exertion

    Time frame: 20 minutes

    RPE (6-20)

  5. Kilocalories utilized

    Time frame: 20 minutes

    kcal/min

  6. Carbohydrate utilized

    Time frame: 20 minutes

    g/min

  7. Fats utilized

    Time frame: 20 minutes

    g/min

Sponsors and collaborators

Lead sponsor

University of Manitoba

Other

Registry information

Official study title

The Effect of Aerobic Exercise With and Without Neuromuscular Electrical Stimulation on Acute Cardiovascular Responses Between Biological Sexes

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jun 11, 2025
Registry last updated
Jun 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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