Acute Cardiovascular Effects of Cigarette Smoking

Twenty healthy smokers will be subjected to measurement of Pulse, Blood Pressure, electrocardiogram (ECG) and Echo at baseline and after smoking a cigarette. The measurements will be compare for any cardiovascular effects of a cigarette smoking on these parameters.

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Key information

Conditions

Smoking Behavior

Age range

18 year and older

Sex eligibility

Male

Study type

Observational

Primary location

Andhra Medical College

Visakhapatnam, Andhra Pradesh, 530002, India

About this study

Twenty male persons habituated to smoking (at least 5 cigarettes/day) will be recruited after an informed consent. Healthy persons with no systemic illness will be included. After a history and a routine examination, subjects will be asked to abstain from smoking for 3 hours and then their pulse, BP, ECG and echo recorded. The measurements will be repeated after 15 min. and the average of these two taken as baseline readings. Then, they will be asked to smoke a cigarette and the measurements taken again. Special focus will be on Doppler measures of left ventricular (LV) function. The measurements are repeated immediately and at 5,10 and 15 min. The data will be analyzed for any cardiovascular effects of smoking a cigarette. Chi square test for proportions and t-test for means will be done. A p value < 0.05 will be taken as significant.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy male smokers (at least 5 cigarettes /day) >18 years old.

Exclusion criteria

Any cardiac or respiratory or systemic illness,including hypertension.

Sponsors and collaborators

Lead sponsor

Andhra Medical College

Other Gov

Registry information

Important dates

Study start: 2002
Primary completion: 2002
Study completion: 2002
First posted: May 4, 2011
Registry last updated: May 4, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed