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NCT Number: NCT05195697

ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care

Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

At Skåne University Hospital approximately 6000 individuals are treated for acute abdominal diseases each year. Given the high number of patients, there is an urgent need to optimize acute surgical care. Lower complication rates would decrease hospital stay, health care costs as well as personal suffering.

Assessment instruments for risks and frailty are not validated for the acute setting and the investigators hypothesize there is room for improvement in prophylactic interventions and risk assessment. The investigators will study cohorts of patients with three different surgical diagnosis: acute pancreatitis, gastrointestinal bleeding and perforated ulcer aiming to identify risk factors for complications or death and to investigate assessment tools in this population. Using propensity score analysis, the investigators will try to identify treatment options associated with better outcome for subcohorts defined by frailty, comorbidity, age or gender. Specific factors of interest include: time to- and kind of treatment, handling of ongoing pharmacological therapy (anticoagulants, corticosteroids) and need for further treatments on a long time basis. The results from this project will be used in a future prospective study where prophylactic treatments and specific treatment options are studied.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients admitted to Skåne University hospital in need of acute surgical care -

Exclusion criteria

Below 18 years old

-

Treatment and study plan

Observational study of different treatments and time to treatment

Other

Different treatment based on the clinical decision

Primary outcomes

  1. Mortality

    Time frame: 5 years

    Defined by Swedish registers

  2. Reintervention

    Time frame: 5 years

    Defined by medical records

  3. Recurrent disease

    Time frame: 5 years

    Defined by medical records

Secondary outcomes

  1. Lengths of hospital stay

    Time frame: 5 years

    defined by medical records

  2. Number of interventions

    Time frame: 5 years

    defined by medical records

  3. complications

    Time frame: 5 years

    defined by medical records and Swedish Registers

Study contacts

Contact information is provided by the study sponsor or research team.

Jenny Eckner, PhD

CONTACT

[email protected]

040 33 10 00

Sara Regnér, PhD

CONTACT

[email protected]

040 33 10 00

Sponsors and collaborators

Lead sponsor

Region Skane

Other

Collaborators

  • Lund University

Registry information

Acronym: ACUTE

Important dates

Study start
2020
Primary completion
2028
Study completion
2030
First posted
Jan 19, 2022
Registry last updated
Jun 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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