Chengdu University of Traditional Chinese Medicine
Chengdu, Sichuan, 610075, China
NCT Number: NCT01686230
This trail aims to evaluate the efficacy of acupoints on the specific meridian for chronic stable angina pectoris, compared with acupoints on the other meridian, sham acupoints and waiting-list. And to confirm the specificity of acupoints on meridian.
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Notify Me35 year–80 year
All sexes
Interventional
Not applicable
Chengdu, Sichuan, 610075, China
The basis of acupuncture is the theory of meridians and acupoints. Meridian and collaterals internally pertain to viscera, and externally spread over the extremities. An acupoint is the place where the visceral qi and meridian qi distributed in. besides acupoints are the stimulus points and reactive points for acupuncture to treat the diseases. Selecting the acupoints on the specific meridian is the basic principle of acupuncture. Recently, as to the existence of specificity of acupoints on the meridian has been questioned by many researchers. This trial using chronic stable angina pectoris as a carrier, select the acupoints on the hand shao yin heart meridian and hand jue yin pericardium meridian to treat chronic stable angina pectoris. Compared with acupoints on the other meridian and non-acupoints ,aiming to evaluate the efficacy, furthermore ,to confirm the existence of the specificity of acupoints on meridian.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
1.Meet the diagnostic criteria of ACC/AHA angina pectoris of coronary heart disease.
2.35 ≤ age ≤ 80 years of age, both male and female.
3.The onset of angina pectoris≥3 months, and the frequency of angina attack≥2 a week.
4.Patients signed the informed consent.
Exclusion criteria
In each session, we treat bilaterally, 3 times a week and 2 days off a week, each patient in the acupuncture treatment groups will receive 12 sessions of acupuncture treatment over 4 weeks. The whole study period is 20 weeks including 4-week baseline period,4-week treatment period, and 12-week follow-up period. we will investigate at 0 day,4week,8week,12week,16week after randomization。
Other names: Electro-acupuncture,Massage
Each group in the basic treatment,Foundation treatment including health education and basic drug therapy.
We recommend lifestyle modification for all patients. Modifications include increasing exercise; limiting alcohol consumption; and weight loss; quit smorking etc.
Basic medication: Aspirin: 100mg qd; Metoprolol:25mg bid; Ramipril:5mg qd; Atorvastatin:20mg qn.
Other names: health education , basic drug therapy
Time frame: 16 weeks after inclusion
The frequency of angina attack during 4-week.
Time frame: 0 day,4, 8, 12, 16 weeks after inclusion
The VAS score evaluation angina pain severity
Time frame: 0 day,4, 8, 12, 16 weeks after inclusion
Time frame: 0 day and 4 weeks after inclusion
Six minute walk test in the evaluation of exercise tolerance
Time frame: 0 day and 4 weeks after inclusion
Dynamic electrocardiogram in six minute walk test to do
Time frame: 0 day,4, 8, 12, 16 weeks after inclusion
Time frame: 0 day,4, 8, 16 weeks after inclusion
Time frame: 4, 8, 12, 16 weeks after inclusion
The incidence of cardiovascular episode during the 4 months(develop into unstable angina, acute myocardial infarction, death)
Time frame: 0 day,4, 8, 16 weeks after inclusion
Chengdu University of Traditional Chinese Medicine
Other
Effect of Acupuncture in Patients With Stable Angina Pectoris: an Open Label, Randomized, Controlled,Multi-center Clinical Study
Acronym: ASAP
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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