Time Gain in the Diagnosis Myocardial Infarction by Troponin Point of Care Testing in the Emergency Room

The investigators prospectively want to compare 3 clinical tests for measuring blood troponin levels in patients presenting to the emergency room with thoracic pain probably related to a myocardial infarction with regard to the time necessary to obtain the test results.

The tests are one laboratory based test and two point of care tests.

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Key information

Conditions

Non STEMI Angina Pectoris Angina Pectoris, Variant Angina, Prinzmetal's Angina, Stable Angina, Unstable Cardiovascular Diseases Chest Pain Heart Diseases Infarction Ischemia Myocardial Infarction Myocardial Ischemia Necrosis Neurologic Manifestations Non-ST Elevated Myocardial Infarction Pain Pathologic Processes Pathological Conditions, Signs and Symptoms Signs and Symptoms Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ziekenhuis Oost-Limburg

Genk, Limburg, 3600, Belgium

About this study

Thoracic pain can be caused by a myocardial infarction. The diagnosis of a myocardial infarction can be made by an ECG (ST-elevation myocardial infarction, STEMI). However, some myocardial infarctions can also occur without ST-elevations on the ECG (non-ST-elevation myocardial infarction, non-STEMI). In the latter case, a quick acquisition of blood troponin levels is necessary to coin the diagnosis and initiate treatment. Therefore, the investigators prospectively want to compare 3 clinical tests for measuring blood troponin levels in patients presenting to the emergency room with thoracic pain probably related to a non-STEMI with regard to the time necessary to obtain the test results.

The 3 tests are:

A laboratory based test: Roche Cobas E 602
A point of care test: Radiometer AQT 90 Flex
A point of care test: Philips Minicare I-20

The measured timeframe is the time between venipuncture to the point the test results are known.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Thoracic pain

Exclusion criteria

Unable to give informed consent

Treatment and study plan

Laboratory based troponin test

Device

acquisition of blood troponin level by Roche Cobas E 603

Point of care based troponin test 1

Device

acquisition of blood troponin level by Radiometer EQT 90 Flex

Point of care based troponin test 2

Device

acquisition of blood troponin level by Philips Minicare I-20

Primary outcomes

time delay until troponin test results are known

Time frame: From the time of venipuncture to the time the troponin test results are known: up to 6 hours

Sponsors and collaborators

Lead sponsor

Ziekenhuis Oost-Limburg

Other

Registry information

Official study title

Time Gain in the Diagnosis of Non-ST Elevation Myocardial Infarction by Troponin Point of Care Testing in the Emergency Room

Acronym: T-POCT

Important dates

Study start: 2017
Primary completion: 2020
Study completion: 2020
First posted: Nov 23, 2016
Registry last updated: Apr 21, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed