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OpenTrials
Completed

NCT Number: NCT07040696

Accuracy of Venous Excess Ultrasound Score at Hospital Admission to Predict Acute Kidney Injury

To evaluate diagnostic accuracy of venous excess ultrasound score to predict acute kidney injury

Completed

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Key information

Conditions

Preeclampsia Acute Kidney Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Hypertension, Pregnancy-Induced Kidney Diseases Male Urogenital Diseases Pre-Eclampsia Pregnancy Complications Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

20 year–40 year

Sex eligibility

Female

Study type

Observational

Primary location

Cairo University

Cairo, Giza Governorate, 6890, Egypt

About this study

Preeclampsia is a common health problem during pregnancy. such condition may result in serious consequences including acute kidney injury. researchers of this study aim to evaluate the ability of venous excess ultrasound score at hospital admission to predict acute kidney injury in preeclampsia with severe features

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • preeclampsia with severe features

Exclusion criteria

  • Patient refusal
  • Preexisting renal impairment (defined as baseline serum creatinine > 1.3 mg/dl)
  • Inability to obtain adequate Doppler views
  • Renal transplantation
  • Previous need for renal replacement therapy
  • Known peripheral vascular disease

Treatment and study plan

Venous excess ultrasound score (VEXUS)

Device

Doppler examination of inferior vena cave, portal vein, hepatic vein, and intrarenal vein will be conducted by an experienced operator

Primary outcomes

  1. The accuracy of VEXUS score at admission to predict acute kidney injury

    Time frame: within 48 hours of admission

Secondary outcomes

  1. need for renal replacement therapy

    Time frame: at 28 days of admission

  2. Cumulative fluid balance

    Time frame: within 48 hours of admission

  3. In hospital mortality

    Time frame: At 28 days of admission

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Accuracy of the Venous Excess Ultrasound Score at Hospital Admission to Predict Acute Kidney Injury in Preeclampsia With Severe Features: A Prospective Observational Study

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 27, 2025
Registry last updated
May 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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