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NCT Number: NCT01376440

Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children

The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water. This goal was adopted in large part because safe drinking water has been seen as critical to fighting diarrheal disease. Source protection is considered the main intervention area to achieve this goal. However, research worldwide that has shown that even drinking water which is safe at the source is subject to frequent and extensive fecal contamination during collection, storage and use in the home. This contamination is through the introduction of cups, dippers or hands, contamination by flies, cockroaches, and rats. Even piped water supplies of adequate microbial quality can pose infectious disease risks if they become contaminated due to unsanitary collection, storage conditions and practices within households.

To reduce this problem, point-of-use water treatment has been advocated as a means to substantially decrease the global burden of diarrhea and to contribute to the MDGs. However, research indicates that there are many unanswered questions around Household water treatment (HWT) that require small or medium scale epidemiological studies and randomized controlled trials, especially with regard to effectiveness, acceptability and identifying suitable target populations. Some of the most urgent questions to be resolved are:(1) How much of the currently cited disease reduction of HWT is due to bias? (2) What is the effect of HWT on nutritional status (weight gain and growth)?(3) At which populations should HWT be targeted? (4) Is it acceptable and sustainable in poor communities where the risk of diarrheal disease is high.

hypothesis: Do household water treatment with chlorine reduce diarrhea among underfive children? hypothesis: Do household water treatment with chlorine acceptable in the community?

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Key information

Conditions

Age range

1 month–59 month

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Kersa district

Kersa, Eastern Hararage, 235, Ethiopia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All children under five years of age in the randomly selected clusters of Kersa district

Exclusion criteria

  • seriously sick children in the randomly selected clusters of Kersa district

Treatment and study plan

household water treatment

Other

household water treatment with 1.25% sodium hypochlorite

Other names: 1.25% sodium hypochlorite

Primary outcomes

  1. To assess the prevalence of diarrhea among under five children

    Time frame: four months

    weekly visit of the household for the presence of diarrhoea among underfive for four months in both the intervention and control groups

Secondary outcomes

  1. To assess the weight gain among the intervention and control groups of under five children

    Time frame: At the beginning and end of the study ( 4 months interval)

    This is designed to assess whether there is weight gain (objective outcome) in children assigned to the intervention group compared to the control group. It is supplement to the prevalence of diarrhea which is subjective outcome for this study

  2. Residual chlorine test

    Time frame: four months

    The use of the intervention (1.25% hypochlorite) is confirmed by the testing the residual chlorine weekly for for months from each household assigned in the intrevention group

Sponsors and collaborators

Lead sponsor

Haramaya Unversity

Other

Registry information

Official study title

Acceptability and Effectiveness of Household Water Chlorination in Reducing the Prevalence of Diarrhea Among Under Five Children in Eastern Ethiopia

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Jun 20, 2011
Registry last updated
Jan 24, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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