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NCT Number: NCT07143630

Abdominal Electrical Stimulation for Balance and Muscle Thickness in Stroke Patients

Stroke is a leading cause of balance impairment and trunk muscle weakness, which restricts independence in daily activities. Neuromuscular electrical stimulation (NMES) is a safe rehabilitation method to activate muscles. This study will evaluate the effects of NMES applied to the abdominal muscles on balance and ultrasound-measured muscle thickness in stroke patients. The findings may provide evidence for new treatment strategies to enhance trunk function and improve quality of life after stroke.

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This study is active but is not currently recruiting participants.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Başakşehir Çam and Sakura City Hospital

Istanbul, 34480, Turkey (Türkiye)

About this study

Stroke is a leading cause of long-term disability and frequently results in impaired balance and trunk muscle weakness, limiting independence in daily life. Abdominal muscles are essential for postural stability, and their weakness may adversely affect mobility and functional outcomes in stroke patients. Neuromuscular electrical stimulation (NMES) is a safe rehabilitation method used to promote muscle contraction and improve strength. While NMES has shown positive effects on limb muscles, its impact on abdominal muscles and balance remains insufficiently studied.

In this prospective randomized controlled trial, participants will be randomly allocated into two groups. The control group will perform core stabilization exercises, while the intervention group will receive core stabilization exercises combined with abdominal NMES. Balance will be assessed using validated clinical scales, and abdominal muscle thickness will be measured by ultrasound. The study aims to determine the additional effects of abdominal NMES on balance, trunk control, and functional recovery in stroke patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 65 years.
  • At least 1 month since the onset of stroke.
  • Ability to maintain sitting balance without support.
  • Ability to stand with or without support.
  • Voluntary agreement to participate in the study (signed informed consent).

Exclusion criteria

  • History of hemiplegia on the contralateral side of the body.
  • Medically unstable condition.
  • History of orthopedic or neurological disease that may cause balance impairment.
  • Presence of balance problems prior to stroke.
  • Body mass index (BMI) ≥ 35
  • Presence of a cardiac pacemaker.
  • Diagnosis of malignancy.
  • Epilepsy.
  • Pregnancy.
  • Open wound or infection in the area where stimulation will be applied.
  • Lack of cooperation or inability to follow instructions.

Treatment and study plan

Neuromuscular Electrical Stimulation

Device

NMES will be applied to the abdominal muscles using a multichannel stimulator. Each session will last approximately 20 minutes, administered 5 times per week for a total of 15 sessions, in addition to core stabilization exercise program performed with the same frequency.

Other names: Chattanooga multichanel stimulator

Core Stabilization Exercises

Behavioral

Participants will perform a structured core stabilization exercise program. The program will be administered 5 times per week for a total of 15 sessions.

Other names: Trunk stabilization training

Primary outcomes

  1. Change in Balance Performance (Berg Balance Scale)

    Time frame: Baseline and after 15 sessions (≈3 weeks)

    Balance will be assessed using the Berg Balance Scale (BBS; maximum score: 56, minimum score: 0). Higher scores indicate better balance, lower scores indicate worse balance.

  2. Abdominal Muscle Thickness (Ultrasound)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

    Abdominal muscle thickness will be measured in millimeters by ultrasound at rest. Higher values indicate greater muscle thickness.

Secondary outcomes

  1. Trunk Control (Trunk Control test)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

  2. Fear of Falling (Visual Analog Scale - VAS)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

    Fear of falling will be evaluated using a Visual Analog Scale (VAS; score range: 0-10 cm, where 0 = no fear and 10 = maximum fear). Higher scores indicate greater fear of falling.

  3. Change in Postural Control (Postural Assessment Scale for Stroke Patients)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

    Postural control will be assessed using the Postural Assessment Scale for Stroke Patients (PASS; score range: 0-36). Higher scores indicate better postural control, lower scores indicate worse control.

  4. Functional Ambulation (Functional Ambulation Classification - FAC)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

    Ambulation will be measured using the Functional Ambulation Classification (FAC; score range: 0-5). Higher scores indicate better functional ambulation.

  5. Mobility (Timed Up and Go Test - TUG)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

    Mobility will be assessed using the Timed Up and Go Test (TUG; measured in seconds). Lower times indicate better mobility, higher times indicate worse mobility.

  6. Motor Recovery (Brunnstrom Stages)

    Time frame: Baseline and after 15 sessions (≈3 weeks)]

    Motor recovery will be assessed using Brunnstrom Stages of Motor Recovery (score range: Stage 1-6). Higher stages indicate better motor recovery.

Sponsors and collaborators

Lead sponsor

Başakşehir Çam & Sakura City Hospital

Other Gov

Registry information

Official study title

Effects of Abdominal Electrical Stimulation on Balance and Ultrasound-Measured Muscle Thickness in Stroke Patients: A Prospective Randomized Controlled Trials

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 27, 2025
Registry last updated
Apr 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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