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NCT Number: NCT07437677

A Survey for Patients and Caregivers Aiming to Understand and Improve the Care of Patients at High Risk of Transfer From Peritoneal Dialysis to Hemodialysis:

Home dialysis is encouraged in Canada and peritoneal dialysis is the most common home dialysis method. However, many patients discontinue peritoneal dialysis, often transferring to hemodialysis. Despite the frequency of this transition, little is known about its impact on patients.

Overall, the UPLIFT-PD program aims to fill this gap by studying the transition from peritoneal dialysis to hemodialysis. The specific goal of this mixed methods sub-study is to conduct a national survey to ask patients and caregivers about priorities and preferences when they anticipate a transfer from peritoneal dialysis to hemodialysis. This survey will be co-created by patient-partners and dialysis experts.

Results from this survey will then be used in other phases of UPLIFT-PD program, detailed in other registrations, which will support people facing a transition from peritoneal dialysis to hemodialysis..

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Key information

Conditions

Peritoneal Dialysis (PD) Hemodialysis Kidney Replacement Therapy Transition

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult (≥18 years)
  • One of the following:
  • Patient who experienced a PD-to-HD transition in past 12 months
  • Patient currently receiving peritoneal dialysis
  • Caregiver (self-defined, including spouses, family members, or friends) of individuals meeting the above criteria
  • Able to read English or French
  • Able to complete the survey in paper or web-based format
  • Able to provide informed consent

Exclusion criteria

  • Age <18 years
  • Unable to provide consent

Treatment and study plan

Primary outcomes

  1. Priorities and Challenges Related to PD-to-HD Transitions

    Time frame: At survey completion (Baseline)

    Measured using Likert-scale responses assessing perceived importance of transition-related factors (e.g. preparedness, timing of discussions, vascular access planning, psychosocial impact). Likert-scale from 0 (lowest importance) to 9 (highest importance)

Secondary outcomes

  1. Preferences for Clinical Scenarios Related to PD-to-HD Transitions

    Time frame: At survey completion (Baseline)

    Assessed using a discrete choice experiment evaluating trade-offs between attributes such as duration on PD, risk of complications, and planned vs. unplanned HD transfer.

  2. Perceptions of Successful Transition

    Time frame: At survey completion (Baseline)

    Agreement with proposed definitions of successful PD-to-HD transitions based on care pathways.

Other outcomes

  1. Qualitative Themes Related to Transition Experiences

    Time frame: At survey completion (Baseline)

    Analysis of open-ended responses to identity key themes and concepts.

Study contacts

Contact information is provided by the study sponsor or research team.

Annie-Claire Nadeau-Fredette, MD MSc

CONTACT

[email protected]

514-252-3400 ext. 6141

Émilie Robitaille

CONTACT

[email protected]

514-252-3400 ext. 5289

Sponsors and collaborators

Lead sponsor

Ciusss de L'Est de l'Île de Montréal

Other

Collaborators

  • Canadian Institutes of Health Research (CIHR)

Registry information

Official study title

Understand, Plan and Improve Care and Wellbeing of Patients at High Risk of Transfer From Peritoneal Dialysis to Hemodialysis - Phase 2 (Survey)

Acronym: ULIFT-PD

Important dates

Study start
2027
Primary completion
2027
Study completion
2029
First posted
Feb 27, 2026
Registry last updated
Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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