A Study to Learn About PRT-064040 Nasal Spray in Healthy Adult Subjects

Inclusion criteria

• Healthy male or female Chinese adults aged ≥18 years and ≤55 years.
• Body Mass Index of 18 to 28 kg/m^2; and a total body weight ≥50 kg for males and ≥45 kg for females.

Exclusion criteria

• History of allergy to any medications, foods, or other substances.
• History or presence of any severe diseases that are considered clinically significant by the investigator.
• Any clinically significant abnormal laboratory test results or positive test.
• Any nasal conditions or diseases that, in the investigator's judgment, may significantly affect the administration or absorption of a nasal product.
• Standard 12-Lead Electrocardiogram that demonstrates clinically relevant abnormalities.
• Pregnant or breastfeeding women, or those with a positive pregnancy test result during screening.
• Positive urine drug screen, alcohol breath test, or nicotine test.
• History of significant alcohol abuse or drug abuse.
• Donation or loss of blood of approximately 400 mL or more within 3 months prior to dosing.
• Previous participation in another clinical trial and receiving the investigational drug within 3 months prior to dosing.