A Study of Uveitis in Children <18 Years of Age

The goal of this observational study is to collect data regarding clinical features and current/past treatments in children under 18 with uveitis. The main questions it aims to answer are:

* What are the frequency of uveitis subtypes in children? * What are clinical and demographic characteristics overall and within each type of uveitis?

Participants will complete one enrollment visit with their doctor. Participants with uveitis onset <6 months from enrollment date will also partake in a 12 month chart review.

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Key information

Conditions

Uveitis Eye Diseases Uveal Diseases

Age range

Up to 17 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age:

Incident cases (onset ≤ 6 months) <17 years
Established cases (onset > 6 months) <18 years
Diagnosis of any type of uveitis (infectious or noninfectious) in any location except traumatic and post-operative uveitis.
Active or inactive uveitis with any treatment status (current / prior / none [but under surveillance]).

Exclusion criteria

Bilateral uveitis with differing etiologies
Traumatic uveitis
Post-operative uveitis
Immediate family member (spouse, biological or legal guardian, child, sibling, parent) who is an investigative site personnel directly affiliated with this study or who is an employee of JAEB Center for Health Research.
Ocular disease related to Retinoblastoma, Coat's disease, retinitis pigmentosa, inherited retinal degeneration, Juvenile xanthogranuloma (JXG), or leukemia/malignancy within the eye.

Treatment and study plan

Primary outcomes

Frequency of uveitis subtypes in children <18 years of age

Time frame: Enrollment

Study contacts

Contact information is provided by the study sponsor or research team.

Julianne Zawadzki, MSPH

CONTACT

[email protected]

813-975-8690

Raymond Kraker, MSPH

CONTACT

[email protected]

8139758690

Sponsors and collaborators

Lead sponsor

Jaeb Center for Health Research

Other

Registry information

Acronym: UV1

Important dates

Study start: 2026
Primary completion: 2027
Study completion: 2028
First posted: Apr 8, 2026
Registry last updated: May 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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