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Completed

NCT Number: NCT00092339

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-190)(COMPLETED)

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

16 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

About this study

The duration of treatment is 1 day.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Impaction of a molar tooth requiring removal

Exclusion criteria

  • Any known allergy to the study drugs

Treatment and study plan

MK0966, rofecoxib

Drug

Comparator: valdecoxib, placebo

Drug

Primary outcomes

  1. Overall analgesic effect as measured by total pain relief over 12 hours.

Secondary outcomes

  1. Overall analgesic effect over 8 hrs.

  2. Time to onset of analgesic, peak analgesic and duration of analgesic effects.

  3. Percent of patients using and amount used of supplemental analgesia within 8, 12, and 24 hrs.

  4. Overall safety and tolerability.

Sponsors and collaborators

Lead sponsor

Merck Sharp & Dohme LLC

Industry

Registry information

Official study title

A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Effects of Rofecoxib 50 mg and Valdecoxib 40 mg in Patients With Postoperative Dental Pain

Important dates

Study start
2002
Primary completion
2002
Study completion
2002
First posted
Sep 27, 2004
Registry last updated
May 9, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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