Recruiting

NCT Number: NCT05849025

A Study of Invasive Hemodynamic for MACHD Registry

This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.

Recruiting

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Key information

Conditions

Healthy Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital Heart Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Heart Defects, Congenital Heart Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic Rochester

Rochester, Minnesota, 55905, United States

Location status: Recruiting

Location contact

ACHD Research Program

CONTACT

(507) 293-2565

Alexander Egbe, MBBS, MPH

CONTACT

[email protected]

(507) 284-2520

Alexander Egbe, MBBS, MPH

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Capacity to Consent
BMI </= 30
Systolic BP </= 140mmHg
Diastolic BP </= 90
eGFR > 30 (within prior 3 months) to confirm kidney function
Able to undergo an MRI

Exclusion criteria

History of Cardiovascular disease that may affect the results of the testing performed.
Any Current orthopedic limitations
Currently taking any cardiac medication
Pregnancy

Treatment and study plan

Primary outcomes

Pulmonary vascular reserve

Time frame: Baseline

The slope of mean pulmonary artery pressure / cardiac output (mPAP/CO)

Study contacts

Contact information is provided by the study sponsor or research team.

ACHD Research Program

CONTACT

(507) 293-2565

Alexander Egbe, MBBS, MPH

CONTACT

[email protected]

(507) 284-2520

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Collaborators

National Heart, Lung, and Blood Institute (NHLBI)

Registry information

Official study title

Invasive Hemodynamic Control Cohort for The Mayo Clinic Adult Congenital Heart Disease (MACHD) Registry

Important dates

Study start: 2023
Primary completion: 2026
Study completion: 2026
First posted: May 8, 2023
Registry last updated: May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed