Altasciences Clinical Company, Inc
Montreal, Quebec, H3P 3P1, Canada
NCT Number: NCT06461039
This study medicine NNC0487-0111 to improve the treatment options for people living with overweight and obesity or with type 2 diabetes. The purpose of the study is to investigate if NNC0487-0111 affects how effective birth control pills are. Participants will take 1-tablet once daily. The study medicine will taken orally for 18 weeks and then study medicine will be injected with a thin needle in a skin fold in the abdomen for 9 weeks.The study will last for about 35 weeks.
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Notify Me18 year–65 year
Female
Interventional
Phase 1
Montreal, Quebec, H3P 3P1, Canada
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Exceptions are routine vitamins, occasional use of acetaminophen, ibuprofen and acetylsalicylic acid, or topical medication not reaching systemic circulation.
NNC0487-0111 A will be administered subcutaneously.
NNC0487-0111 C will be taken orally.
Levonorgestrel 150 μg + Ethinylestradiol 30 μg (Oral contraceptive OC) will be taken orally.
Acetaminophen - 500 mg/15 ml will be taken orally.
Time frame: Day 8 and Day 193
Measured as hours picograms per milliliter (h*pg/mL).
Time frame: Day 8 and Day 193
Measured as hours picograms per milliliter (h*pg/mL).
Time frame: Day 8 and Day 193
Measured as picograms per milliliter (pg/mL).
Time frame: Day 8 and Day 193
Measured as picograms per milliliter (pg/mL).
Time frame: Day 8 and Day 135
Measured as hours picograms per milliliter (h*pg/mL).
Time frame: Day 8 and Day 135
Measured as hours picograms per milliliter (h*pg/mL).
Time frame: Day 8 and Day 135
Measured as picograms per milliliter (pg/mL).
Time frame: Day 8 and Day 135
Measured as picograms per milliliter (pg/mL).
Time frame: Day 1 and Day 186
Measured as hours micro grams per milliliter (h*μg/mL).
Time frame: Day 1 and Day 186
Measured as hours micro grams per milliliter (h*μg/mL).
Time frame: Day 1 and Day 186
Measured as micrograms per milliliter (μg/mL).
Time frame: Day 1 and Day 128
Measured as hours micro grams per milliliter (h*μg/mL).
Time frame: Day 1 and Day 128
Measured as hours micro grams per milliliter (h*μg/mL).
Time frame: Day 1 and Day 128
Measured as micrograms per milliliter (μg/mL).
Novo Nordisk A/S
Industry
Investigation of the Effect of NNC0487-0111 on Pharmacokinetics of an Oral Combination Contraceptive (Ethinylestradiol and Levonorgestrel) and Gastric Emptying in Females of Non-childbearing Potential
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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