A Randomized, Double Blind, Placebo-controlled Study to Assess the the Preemptive Benefit of Etoricoxib in Patients Receiving Anterior Cruciate Ligament Reconstruction

Post surgical pain associated with ligament reconstruction may persist for few days after the surgical procedure. Arcoxia is a new anti-inflammatory and analgesic drug that alleviate pain through oral administration. This study will test the safety and efficacy of Arcoxia in the management of post-operational pain in patients receive the ligament reconstruction surgery.

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Key information

Conditions

Post-operational Pain Athletic Injuries Wounds and Injuries

Age range

16 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

National Taiwan University Hospital

Taipei, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Men and women age ranged from 16~35 who have anterior cruciate ligament injury and/or associated injuries are scheduled for ACL reconstruction surgery.
Patient agrees to participate into this study and is willing to sign the patient informed consent form.

Treatment and study plan

Arcoxia(etoricoxib 90 mg/tablet)

Drug

Arcoxia(etoricoxib 90 mg/tablet) or placebo, #1, 3 days

Primary outcomes

Pain at rest at different timepoint after surgical procedures

Time frame: From baseline(preoperation) to 3 days after

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Collaborators

Merck Sharp & Dohme LLC

Registry information

Important dates

Study start: 2008
Primary completion: 2010
Study completion: 2010
First posted: Nov 6, 2007
Registry last updated: Jun 22, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed