A Parallel Study Evaluating the Effect of A-F Betafood® on Gallbladder and Liver Function.

Inclusion criteria

• Females 40-75 years of age or older not of child bearing potential. Defined as females who have had a hysterectomy or oophorectomy, bilateral tubal ligation or are post-menopausal (natural or surgically with > 1 year since last menstruation).OR Female subject of childbearing potential must agree to use a medically approved method of birth control and have a negative urine pregnancy test result
• BMI of 25.0 kg/m2 to 29.9 kg/m2
• Agrees to comply with study procedures
• Healthy as determined by laboratory results, medical history and physical exam
• Has given voluntary, written, informed consent to participate in the study
• Gastrointestinal distress with various fatty foods as determined by the modified GSRS questionnaire
• Family history of gallbladder disease or previous history of gallbladder attacks
• Has a normal resting heart rate 50-80bpm

Exclusion criteria

• Women who are pregnant, breastfeeding, or planning to become pregnant during the course of the trial
• Unstable psychiatric disorder requiring hospitalization within past 6 months
• Use of prescription medications, over the counter medications or natural health products/dietary supplements known to affect gastric/gastrointestinal function within 4 weeks of randomization
• Presence of gallstones as determined by ultrasound
• Uncontrolled hypertension defined as untreated systolic blood pressure > 160 mmHg and/or diastolic blood pressure > 100 mmHg
• Clinically significant abnormal laboratory results at screening including: AST, ALT and/or bilirubin > 2 x the ULN; Serum creatinine >1.5 x the ULN or eGFR < 60; Hemoglobin < 123 g/L
• Participation in a clinical research trial within 30 days prior to randomization
• Allergy or sensitivity to test article ingredients, soy, dairy, egg, wheat, peanut, tree nuts, fish or shellfish.
• Individuals who are cognitively impaired and/or who are unable to give informed consent
• Any other condition which in the Investigator's opinion may adversely affect the subject's ability to complete the study or its measures or which may pose significant risk to the subject