A Comparison of Exhaled Carbon Monoxide Measurements Using the iCOquit Smokerlyzer and Vitalograph Breath CO Monitor vs Carboxyhemoglobin From Venous Samples While Validating a Mobile Research Application

Inclusion criteria

• Has signed the ICF and is able to read and understand the information provided in the ICF.
• Is 21 to 65 years of age (inclusive) at screening.
• No intention of quitting smoking in the next 30 days.
• Willing and able to comply with the requirements of the study.
• Owns a smartphone running iOS or Android with text message and data capabilities compatible with the eResearch app.

Exclusion criteria

• Is unhealthy or cannot participate in the study for any reason (e.g., medical, psychiatric, and/or social reason) as judged by the Investigators or designated medical staff based on all available assessments from the screening period (e.g., vital signs, physical examination, concomitant medications and medical history).
• PHQ-9 score greater than 9, or a score greater than 0 on item #9 ("Thoughts you would be better off dead, or of hurting yourself in some way") at screening.
• Body mass index (BMI) greater than 40.0 kg/m2
• Use of any of these products in the past 30 days:

• Illegal drugs (or if the urine drug screen is positive for cocaine, THC, amphetamines, methamphetamines, or opiates),
• Experimental (investigational) drugs that are unknown to participant,
• Chronic opioid use.
• Pregnant or nursing (by self-report) or positive urine pregnancy test.
• Participant enrollment numbers met.

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