A Bioequivalence Study of Subcutaneous (SC) Lebrikizumab Administered by Needle and Syringe or by Prefilled Syringe With Needle Safety Device (PFS-NSD)

Inclusion criteria

• Healthy adults 18 to 65 years of age, inclusive
• Body mass index (BMI) 18 to 32 kg/m^2 and body weight 50 to 100 kg, inclusive
• Nonpregnant and nonlactating females
• Agreement to utilize effective contraception among men and women of childbearing potential

Exclusion criteria

• Known allergy or hypersensitivity to study drug or components
• History of alcohol or drug abuse within 12 months prior to study drug, or positive test for alcohol or drugs of abuse
• Receipt of an investigational agent within 30 days of 5 half-lives prior to Day -1
• Biological therapy within 90 days prior to Day -1
• Parasitic or Listeria monocytogenes infection within 6 months prior to Screening
• Receipt of blood products within 2 months prior to study entry
• Donation or loss of blood/plasma within up to 6 months prior to study drug, depending upon volume
• Receipt of live attenuated vaccine within 1 month prior to study drug
• Use of tobacco- or nicotine-containing products within 14 days prior to Screening
• Use of any prescription or nonprescription medication within 14 days prior to study drug