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Completed

NCT Number: NCT07800169

Factors Affecting Postoperative Recovery From Common Bile Duct Cysts in Children: A Multicenter Retrospective Analysis Based on Perioperative Clinical Characteristics

This retrospective study aims to systematically analyze the factors influencing short-term rehabilitation and liver function recovery after radical surgery for pediatric common bile duct cysts, identify independent risk factors, construct a risk prediction model, and provide an evidence-based basis for optimizing perioperative management.

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Key information

Age range

1 week–16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Wuhan Children'c Hospital

Wuhan, Hubei, 430016, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 0-16 years, meeting the age-based classification criteria for pediatric patients; 2) Diagnosis of common bile duct cyst confirmed by imaging studies (liver and gallbladder ultrasonography, MRCP, or CT), with histological typing performed according to the Todani classification system; 3) First-time surgical resection of the common bile duct cyst combined with radical Roux-en-Y hepatojejunal anastomosis; 4) Complete clinical medical records, preoperative laboratory test data, intraoperative surgical documentation, postoperative rehabilitation and follow-up data; 5) The study cases are affiliated with respective participating research centers, and inpatient and follow-up data can be readily retrieved.

Exclusion criteria

  • Children with severe end-stage liver cirrhosis, irreversible liver failure, or malignant biliary tract tumors; 2) Children with severe multi-organ failure (e.g., cardiac, pulmonary, or renal failure) who cannot be adequately assessed for surgical prognosis; 3) Children undergoing secondary surgery or those with recurrent choledochal cysts; 4) Children who have only undergone palliative stoma creation or percutaneous drainage without receiving radical surgical intervention; 5) Cases in which critical perioperative clinical data are missing, making it impossible to meet the requirements for data analysis.

Treatment and study plan

Primary outcomes

  1. First flatus time (hours)

    Time frame: From the date of surgery until the date of first flatus, assessed up to 7 days postoperatively.

  2. First defecation time

    Time frame: From the date of surgery until the date of first defecation, assessed up to 7 days postoperatively.

  3. Postoperative length of hospital stay (days)

    Time frame: From the date of surgery until the date of hospital discharge, assessed up to 3 months postoperatively.

Sponsors and collaborators

Lead sponsor

Wuhan Children's Hospital

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Sep 2, 2026
Registry last updated
Sep 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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