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NCT Number: NCT07798830

Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty

This study aims to compare the analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided deep iliacus plane block (DIPB) and transmuscular quadratus lumborum block (QLB) in patients undergoing total hip arthroplasty (THA).

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Key information

Conditions

Deep Iliacus Plane Block Postoperative Analgesia Total Hip Arthroplasty Transmuscular Quadratus Lumborum Block

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location status: Recruiting

Location contact

Mohammed S Elsharkawy, MD

CONTACT

[email protected]

00201148207870

About this study

Total hip arthroplasty (THA) is one of the most commonly performed orthopedic procedures for the treatment of end-stage hip disorders. It is indicated for conditions such as osteoarthritis, rheumatoid arthritis, avascular necrosis, and femoral neck fractures.

The quadratus lumborum block (QLB) is an ultrasound-guided fascial plane block that has been increasingly used for analgesia in hip surgery.

The deep iliacus plane block (DIPB) is a recently introduced regional anesthesia technique specifically developed for hip analgesia. The block is performed by depositing local anesthetic in the deep fascial plane between the iliacus muscle and the iliac bone.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years.
  • Both sexes.
  • American Society of Anesthesiologists (ASA) physical status I-III.
  • Scheduled for elective unilateral total hip arthroplasty (THA) under spinal anesthesia.

Exclusion criteria

  • Known allergy to local anesthetics or study medications.
  • Coagulopathy or anticoagulant therapy contraindicating regional anesthesia.
  • Infection at the site of injection.
  • Pre-existing neurological deficits affecting the lower limbs.
  • Chronic opioid use or opioid dependence.
  • Severe hepatic, renal, respiratory, or cardiac disease.
  • Body mass index (BMI) > 40 kg/m².
  • Contraindications to spinal anesthesia.

Treatment and study plan

Deep iliacus plane block

Drug

Patients will receive ultrasound-guided deep iliacus plane block (DIPB) using 25 mL of 0.25% bupivacaine.

Quadratus lumborum block

Drug

Patients will receive ultrasound-guided transmuscular quadratus lumborum block (QLB) using 25 mL of 0.25% bupivacaine.

Primary outcomes

  1. Degree of pain

    Time frame: Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed at post-anesthesia care unit (PACU), 2, 4, 6, 12, and 24 h postoperatively.

Secondary outcomes

  1. Total morphine consumption

    Time frame: 24 hours postoperatively

    Rescue analgesia of morphine will be given as 3 mg bolus if the Visual Analog Scale (VAS) > 3 to be repeated after 30 min if pain persists until the VAS < 4.

  2. Time to the 1st rescue analgesia

    Time frame: 24 hours postoperatively

    Time to the first request for the rescue analgesia will be recorded from the end of block to first dose of morphine administrated.

  3. Time for ambulation

    Time frame: 24 hours postoperatively

    Time to ambulation: the time interval (in hours) from the end of surgery to the first successful mobilization of the patient, defined as the ability to stand and walk at least 3-5 steps with or without assistance

  4. Length of hospital stay

    Time frame: 24 hours postoperatively

    Length of hospital stay will be recorded from admission till the discharge from hospital.

  5. Incidence of adverse events

    Time frame: 24 hours postoperatively

    Incidence of adverse events such as bradycardia, hypotension, nausea, vomiting, respiratory depression, or any other complication will be recorded.

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammed S Elsharkawy, MD

CONTACT

[email protected]

00201148207870

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty: A Randomized Clinical Trial

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Sep 1, 2026
Registry last updated
Sep 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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