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Completed

NCT Number: NCT06003738

Postoperative Analgesia After Total Hip Arthroplasty: Comparative Evaluation of Pericapsular Nerve Group Versus Fascia Iliaca Compartment Block

The aim of this study is to compare the effectiveness of pericapsular nerve group (PENG) block versus fascia iliaca compartment block (FICB) for postoperative pain relief following total hip arthroplasty (THA).

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain shams University

Cairo, 11588, Egypt

About this study

Total hip arthroplasty is a widely used surgical treatment intervention for treating hip conditions such as femur neck fractures and advanced hip osteoarthritis.

Hip fractures are quite common, regardless of the age of the population (young or old), and they are extremely painful. A hip fracture is a serious injury with potentially life-threatening complications, and it is a common orthopedic emergency in elderly individuals. Early surgery within 48 hours of a fracture has been found to lower mortality and complication rates.

The pericapsular nerve group block is a novel regional analgesia technique to decrease pain after total hip arthroplasty (THA) while preserving the motor function. The local anaesthetic is deposited using this method in the fascial plane between the psoas muscle and the superior pubic ramus, which aims sensory branches of the obturator, accessory obturator, and femoral nerves in the anterior capsule of the hip.

Fascia iliaca compartment block, for procedures on the femur and hip joint, is still a well-liked regional anaesthetic technique. Studies have found that FICB prevents complications by anaesthetizing the femoral nerve far from critical neurovascular structures while still giving enough analgesia.

Both blocks could be used to effectively reduce pain intensity up to 24 hours, total opioid consumption, and length of hospital stay in THA patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age from 18 to 80 years.
  • Both sexes.
  • American Society of Anaesthesiologists (ASA) Physical Status II-III.
  • Scheduled for Total hip arthroplasty (THA) under spinal anesthesia.

Exclusion criteria

  • Patients' refusal
  • Contraindications to spinal anesthesia or nerve blocks.
  • History of allergy to the medications used in the study.
  • Pregnancy.
  • Significant cognitive impairment.

Treatment and study plan

Fascia iliaca compartment block

Other

Patients received an ultrasound-guided supra-inguinal fascia iliaca compartment block.

Pericapsular nerve group block

Other

Patients received an ultrasound-guided pericapsular nerve group (PENG) block.

Primary outcomes

  1. Degree of pain

    Time frame: 24 hours postoperatively

    Degree of pain was assessed using the Visual Analogue Scale (VAS). VAS is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain. VAS was recorded at 0, 2, 4, 6, 12, 18, and 24 hours postoperatively.

  2. Total amount of nalbuphine consumption

    Time frame: 24 hours postoperatively

    If the postoperative Visual Analogue Scale (VAS) was greater than 3, an intravenous dose of 5 mg Nalbuphine diluted in 5 mL of saline was administered as needed.

  3. Number of cases needing rescue doses

    Time frame: 24 hours postoperatively

    The number of cases needing rescue doses was recorded.

Secondary outcomes

  1. Postoperative ambulation

    Time frame: 24 hours postoperatively

    Time from completion of surgery to first assisted standing and walking ≥2 meters was recorded as the ambulation time.

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Postoperative Analgesia After Total Hip Arthroplasty: Comparative Evaluation of Pericapsular Nerve Group Versus Fascia Iliaca Compartment Block in a Randomized Controlled Trial

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Aug 22, 2023
Registry last updated
Aug 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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