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NCT Number: NCT07283185

Prospective Comparison of the Carbon Footprint of EUS vs MRCP for Evaluation of Suspected Choledocholithiasis

MRCP and EUS are diagnostically equivalent in detecting CBD stones among patients with intermediate risk, as shown in a landmark RCT. However, MRI-based imaging is power-intensive, requiring large infrastructure and long scan durations. EUS, a less energy-consuming and portable procedure, has the added advantage of enabling same-session ERCP, reducing the need for repeat procedures.

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Key information

Conditions

Choledocholithiasis Bile Duct Diseases Biliary Tract Diseases Cholelithiasis Common Bile Duct Diseases Digestive System Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

AIG Hospitals

Hyderabad, Telangana, 500032, India

Location status: Recruiting

About this study

MRCP and EUS are diagnostically equivalent in detecting CBD stones among patients with intermediate risk, as shown in a landmark RCT. However, MRI-based imaging is power-intensive, requiring large infrastructure and long scan durations. EUS, a less energy-consuming and portable procedure, has the added advantage of enabling same-session ERCP, reducing the need for repeat procedures. Prior research confirms that diagnostic EUS generates significantly less CO₂e per procedure compared to radiologic imaging. This study aims to support sustainable diagnostic choices by quantifying their environmental footprint.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years
  • Intermediate likelihood of CBD stone (per ESGE)
  • Undergoing either MRCP or EUS for evaluation

Exclusion criteria

  • High or low likelihood category (per ESGE)
  • Undergoing both MRCP and EUS simultaneously
  • Contraindications to either modality

Treatment and study plan

Primary outcomes

  1. Total kg CO₂e per procedure for EUS vs MRCP.

    Time frame: 12 months

    Total kg CO₂e per procedure for EUS vs MRCP.

Secondary outcomes

  1. Emissions

    Time frame: 12 months

    Emissions per accurate diagnosis Emissions broken down by source (electricity, consumables, travel) Recommendations for sustainable diagnostic practices

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Asian Institute of Gastroenterology, India

Other

Registry information

Official study title

Prospective Comparison of the Carbon Footprint of Endoscopic Ultrasound (EUS) vs Magnetic Resonance Cholangiopancreatography (MRCP) for Evaluation of Suspected Choledocholithiasis

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 15, 2025
Registry last updated
Jan 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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