Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia

Intraoperative anesthetic management for total knee replacement (TKR) can be performed under general or spinal anesthesia. These two techniques have their own characteristics and may impact postoperative recovery differently. However, there are no studies in the literature analyzing postoperative functional recovery after TKR surgery according to the type of anesthesia. The objective of this study is to compare postoperative recovery, assessed by the QoR-15F score, in patients undergoing TKR under spinal anesthesia versus surgery under general anesthesia.

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Key information

Conditions

Total Knee Replacement

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Service d'Anesthésiologie - Réanimation Chirurgicale - CHU de Strasbourg - France

Strasbourg, 67091, France

Location status: Recruiting

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male or female, 18 years of age or older (no upper age limit)
Underwent total knee replacement surgery between January 1, 2020 and June 30, 2023
Assessed using the QoR-15F score

Exclusion criteria

Subject (and/or their legal representative, if applicable) who expressed their opposition to the reuse of their data for scientific research purposes.
Revision, emergency, oncological, bilateral, or septic surgery

Treatment and study plan

Primary outcomes

QoR-15F score

Time frame: at Day 1, Day3, Day 14, and Day 28 postoperatively

Interested in participating?

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Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Official study title

Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia: A Retrospective Single-Center Observational Comparative Superiority Study

Acronym: PTG-RachiVsAG

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Dec 10, 2025
Registry last updated: Dec 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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