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NCT Number: NCT06520137

Third Molars Extraction and Periodontal Disease

The aim of the study is to evaluate the changes in periodontal conditions on the distal aspect of the second maxillary molar after the extraction of the maxillary wisdom tooth. As secondary outcome patient- related and tooth-related factors will be analysed to evaluate their effects on the periodontal varibales during time.

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Key information

Conditions

Periodontal Diseases Mouth Diseases Stomatognathic Diseases

Age range

19 year–64 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Siena

Siena, Italy/SI, 53100, Italy

Location status: Recruiting

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age more than 18 years or older
  • Presence of an impacted upper wisdom tooth that need to undergo surgical extraction
  • Participants need to be able to sign and understand the informed consent and to follow the study-related procedures.

Exclusion criteria

  • People that have compromised general health conditions (ASA 3, 4, 5, 6)
  • Patients that assumed antibiotics in the last 6 months
  • Pregnant or breastfeeding women
  • Patients who suffer from periodontitis stage III and IV
  • Presence of a third molar with incomplete root formation is not taken into account for the surgical extraction.
  • Smoker patients

Treatment and study plan

Tooth extraction

Procedure

Extraction of maxillary third molars

Primary outcomes

  1. Probing Pockeet Depth (PPD)

    Time frame: Baseline, 1 month, 6 months, 12 months, 24 months

    Distance between the free gingival margin and the apical location of the probe's tip.

  2. Bone Level (BL)

    Time frame: Baseline, 1 month, 6 months, 12 months, 24 months

    Distance between the bone crest and the cemento-enamel junction (CEJ)

Secondary outcomes

  1. Type of impaction

    Time frame: Baseline

    According to Archer's classification it is possible to have seven types of impaction: mesio-angular, disto-angular, bucco-angular, linguo-angular, horizontal, vertical, inverted.

  2. Clinical Attachment Level (CAL)

    Time frame: Baseline, 1 month, 6 months, 12 months, 24 months

    Distance between the cemento-enamel junction and the apical location of the probe's tip

  3. Recession (REC)

    Time frame: Baseline, 1 month, 6 months, 12 months, 24 months

    Distance between the free gingival margine and the cemento-enamel junction (CEJ)

  4. Keratinized Tissue (KT)

    Time frame: Baseline, 1 month, 6 months, 12 months, 24 months

    Distance between the muco-gingival line and the free gingival margin

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Azienda Ospedaliera Universitaria Senese

Other

Registry information

Official study title

Correlation Between Upper Third Molars Extraction and Upper Second Molars Periodontal Disease: a Prospective Clinical Observational Study

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jul 25, 2024
Registry last updated
Jul 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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