NMD670
DrugTablets taken twice a day for 21 days
NCT Number: NCT06414954
This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, administered twice a day (BID) for 21 days.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Phase 2
UZ Leuven, Leuven, Belgium
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Tablets taken twice a day for 21 days
Tablets taken twice a day for 21 days
Time frame: Baseline to day 21
Scale goes from 0-39 and higher score indicates worse symptomatology
Time frame: Baseline to day 21
Scale goes from 0-24 and higher score indicates worse symptomatology
Time frame: Baseline to day 21
Scale goes from 0-50 and higher score indicate worse symptomatology
Time frame: Baseline to day 21
Scale goes from 0-30 and higher score indicate worse quality of life
Time frame: Baseline to day 21
Scale goes from 8-40 and higher score indicate worse symptomalogy
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: Over 21 days of dosing
Summarised per treatment
Time frame: From screening (day -28 to day -1) until follow up (day 28)
Summarised per treatment
Contact information is provided by the study sponsor or research team.
NMD Pharma A/S
Industry
A Phase 2b, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 3 Dose Levels of NMD670 Over 21 Days in Adult Patients With AChR/MuSK-Ab+ Myasthenia Gravis
Acronym: SYNAPSE-MG
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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