Trial on Vascular Inflammation in Atopic Dermatitis

Main inclusion Criteria:

• Men or women
• 18 years of age or older at time of consent.
• For AD subjects only: Confirmed clinical diagnosis of active AD according to Hanifin and Rajka criteria, BSA, EASI and IGA.
• For AD subjects only: Diagnosis of atopic dermatitis for at least 5 years.
• Women of childbearing potential is willing to use effective contraceptive method.
• Women of childbearing potential must have a negative urine pregnancy test.

Main exclusion Criteria:

• Has known cardiovascular arterial disease, a pacemaker, psoriasis, uncontrolled diabetes.
• Presence of an unstable co-morbidity that could have an effect on vascular inflammation.
• Heart rate restriction for patients with asthma or COPD.
• Use of any topical medication for atopic dermatitis on the site to be biopsied.
• Use of systemic treatments for atopic dermatitis.
• Use of phototherapy, tanning booth or other ultraviolet light sources.
• Use of biologics.
• Use of experimental medications.