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Clinical trial condition

Scleroderma, Systemic

Explore clinical trials studying Scleroderma, Systemic. Study availability and eligibility vary by location and protocol.

433 public trials 124 recruiting studies
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Scleroderma, Systemic trial results

Recruiting

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

NCT03816345

Conditions
Arthritis, Arthritis, Psoriatic, Arthritis, Rheumatoid, +59 more
Locations
  • University of Alabama at Birmingham Cancer Center Birmingham, Alabama, United States
  • Stanford Cancer Institute Palo Alto Palo Alto, California, United States
  • University of California Davis Comprehensive Cancer Center Sacramento, California, United States
  • Smilow Cancer Center/Yale-New Haven Hospital New Haven, Connecticut, United States
View all 52 locations
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Recruiting

Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis

NCT06954597

Conditions
Connective Tissue Diseases, Digital Ulcers in Systemic Sclerosis, Scleroderma, Systemic, +3 more
Locations
  • Centre Hospitalier Universitaire de Bordeaux, Service de Rhumatologie Bordeaux, France
  • CHU Grenoble Alpes La Tronche, France
  • CHRU Lille, Hôpital Claude Huriez, Rue Michel Polonosvski Lille, France
  • AP-HP Hôpital Cochin Paris, France
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Recruiting

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

NCT07335562

Conditions
Connective Tissue Diseases, Scleroderma, Systemic, Skin Diseases, +2 more
Locations
  • Local Institution - 0035 Scottsdale, Arizona, United States
  • University of Colorado Anschutz Medical Campus Aurora, Colorado, United States
  • Local Institution - 0001 Denver, Colorado, United States
  • Local Institution - 0069 Miami, Florida, United States
View all 56 locations
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Recruiting

US Zamto-cel Autoimmune Diseases

NCT06708845

Conditions
Autoimmune Diseases, Connective Tissue Diseases, Diffuse Cutaneous Systemic Sclerosis, +17 more
Locations
  • Froedtert Hospital and the Medical College of Wisconsin Milwaukee, Wisconsin, United States
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Recruiting

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

NCT06733935

Conditions
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Arthritis, +23 more
Locations
  • Nkarta Investigational Site Orange, California, United States
  • Nkarta Investigational Site Gainesville, Florida, United States
  • Nkarta Investigational Site Miami, Florida, United States
  • Nkarta Investigational Site Plantation, Florida, United States
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Recruiting

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

NCT06308978

Conditions
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV), Autoimmune Diseases, +28 more
Locations
  • Wallace Rheumatic Center Beverly Hills, California, United States
  • Providence Medical Foundation Fullerton, California, United States
  • University of California Irvine Irvine, California, United States
  • Children's Hospital Los Angeles Division Of Rheumatology Los Angeles, California, United States
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Recruiting

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

NCT06991114

Conditions
Arthritis, Arthritis, Rheumatoid, Autoimmune Diseases, +29 more
Locations
  • Artiva Investigational Site Tuscaloosa Tuscaloosa, Alabama, United States
  • Artiva Investigational Site Phoenix Phoenix, Arizona, United States
  • Artiva Investigational Site Tucson Tucson, Arizona, United States
  • Artiva Investigational Site Chula Vista Chula Vista, California, United States
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