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Clinical trial condition

Primary Mediastinal Lymphoma

Explore clinical trials studying Primary Mediastinal Lymphoma. Study availability and eligibility vary by location and protocol.

6 public trials 2 recruiting studies
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Primary Mediastinal Lymphoma trial results

Completed

Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors

NCT03010982

Conditions
Advanced Solid Tumors, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, +17 more
Locations
  • The Clatterbridge Cancer Centre NHS Foundation Trust Bebington, Wirral, United Kingdom
  • Royal Liverpool and Broadgreen University Hospital Trust Liverpool, United Kingdom
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Completed

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

NCT03028103

Conditions
Advanced Solid Tumor, Diffuse Large B Cell Lymphoma, Hemic and Lymphatic Diseases, +15 more
Locations
  • University of Arizona Cancer Center Tucson, Arizona, United States
  • Moffitt Cancer Center Tampa, Florida, United States
  • Columbia University Medical Center New York, United States
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