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Clinical trial condition

Neurodegenerative Diseases

Explore clinical trials studying Neurodegenerative Diseases. Study availability and eligibility vary by location and protocol.

9,035 public trials 1,770 recruiting studies
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Neurodegenerative Diseases trial results

Completed

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)

NCT01839656

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Stanford University Medical Center Stanford, California, United States
  • Nemours Children's Hospital Orlando, Florida, United States
  • Columbia University Medical Center New York, United States
  • The Hospital for Sick Children (SickKids) Toronto, Ontario, Canada
View Trial Details
Completed

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)

NCT02292537

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • UCLA Clinical and Translational Research Center Los Angeles, California, United States
  • Lucile Packard Children's Hospital at Stanford Palo Alto, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Nemours Children's Hospital Orlando, Florida, United States
View all 24 locations
View Trial Details
Completed

The SUSTAIN Study Compares the Effects of Sustained and Immediate-release Pramipexole on the noctUrnal Symptoms of paTients With Advanced ParkInsoN's Disease Who Also Take L-Dopa

NCT03521635

Conditions
Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, +6 more
Locations
  • Peking Union Medical College Hospital Beijing, China
  • Beijing Hospital Beijing, China
  • West China Hospital Chengdu, China
  • The First Afiliated Hospital, Sun Yet-sen University Guangzhou, China
View Trial Details
Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)

NCT02052791

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
  • UT Southwestern Medical Center - Children's Medical Center Dallas Dallas, Texas, United States
  • University of Utah School of Medicine Salt Lake City, Utah, United States
View Trial Details
Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)

NCT01780246

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +5 more
Locations
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Columbia University Medical Center New York, United States
  • UT Southwestern Medical Center - Children's Medical Center Dallas Dallas, Texas, United States
  • University of Utah School of Medicine Salt Lake City, Utah, United States
View Trial Details
Completed

Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas

NCT01767792

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Cranial Nerve Neoplasms, +26 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • Children's National Medical Center Washington D.C., District of Columbia, United States
  • Children's HealthCare of Atlanta Atlanta, Georgia, United States
  • University of Chicago Chicago, Illinois, United States
View Trial Details

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