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Clinical trial condition

Neurodegenerative Diseases

Explore clinical trials studying Neurodegenerative Diseases. Study availability and eligibility vary by location and protocol.

9,104 public trials 1,784 recruiting studies
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Neurodegenerative Diseases trial results

Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN

NCT05309668

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +14 more
Locations
  • Research Site Akron, Ohio, United States
  • Research Site Philadelphia, Pennsylvania, United States
  • Research Site Houston, Texas, United States
  • Research Site Richmond, Virginia, United States
View all 16 locations
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Active, not recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

NCT03871257

Conditions
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, Heredodegenerative Disorders, Nervous System, +16 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Banner Children's at Desert Mesa, Arizona, United States
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
View all 132 locations
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Active, not recruiting

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

NCT06402838

Conditions
Alzheimer Disease, Alzheimer's Disease, Brain Diseases, +7 more
Locations
  • Centro de Investigación Clínica UC-CICUC Santiago, Chile
  • Hospital Clinico Univ de Chile Santiago, Chile
  • Aarhus Universitetshospital Skejby Aarhus N, Denmark
  • Rigshospitalet, Hukommelsesklinikken Koebenhavn Oe, Denmark
View all 46 locations
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Active, not recruiting

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

NCT06517758

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis, +11 more
Locations
  • Honor Health Research Institute Scottsdale, Arizona, United States
  • Fullerton Neuro and Headache Ctr Fullerton, California, United States
  • California Pacific Medical Center Sacramento, California, United States
  • Augusta University Georgia Augusta, Georgia, United States
View all 116 locations
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Active, not recruiting

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

NCT05686551

Conditions
Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, +13 more
Locations
  • Uab Medicine Birmingham, Alabama, United States
  • Barrow Neurological Institute Phoenix, Arizona, United States
  • University of California Davis Medical System Sacramento, California, United States
  • CenExel Rocky Mountain Clinical Research, LLC Englewood, Colorado, United States
View all 70 locations
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Active, not recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

NCT05531656

Conditions
Alzheimer Disease, Brain Diseases, Central Nervous System Diseases, +7 more
Locations
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • Banner Alzheimer's Institute Phoenix, Arizona, United States
  • Banner Sun Health Research Institute Sun City, Arizona, United States
  • University of California Irvine, California, United States
View all 50 locations
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