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Clinical trial condition

Neurodegenerative Diseases

Explore clinical trials studying Neurodegenerative Diseases. Study availability and eligibility vary by location and protocol.

9,146 public trials 1,794 recruiting studies
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Neurodegenerative Diseases trial results

Recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

NCT06351592

Conditions
Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Central Nervous System Diseases, +10 more
Locations
  • Concord Repatriation General Hospital Concord, New South Wales, Australia
  • Macquarie University Sydney, New South Wales, Australia
  • Sunshine Coast University Hospital Birtinya, Queensland, Australia
  • KU Leuven Leuven, Vlaams-Brabant, Belgium
View all 22 locations
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Recruiting

Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

NCT07287397

Conditions
Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Metabolic Diseases, +8 more
Locations
  • St Joseph's Hospital and medical Center - Barrow Neurological Institute Phoenix, Arizona, United States
  • University of California San Diego Medical Center San Diego, California, United States
  • Mayo Clinic in Florida Jacksonville, Florida, United States
  • University of Miami School of Science Miami, Florida, United States
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Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

NCT05861999

Conditions
Central Nervous System Diseases, Motor Neuron Disease, Muscular Atrophy, Spinal, +4 more
Locations
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Valley Children's Hospital Madera, California, United States
  • Stanford Univ Medical Center Palo Alto, California, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
View all 19 locations
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Recruiting

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

NCT07717411

Conditions
Alzheimer Disease, Alzheimer's Disease, Brain Diseases, +7 more
Locations
  • Irvine Center for Clinical Research Irvine, California, United States
  • Syrentis Clinical Research Santa Ana, California, United States
  • K2 Medical Research, LLC Maitland, Florida, United States
  • Basil Clinical Laurelton, New York, United States
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Recruiting

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

NCT07432958

Conditions
Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, +10 more
Locations
  • University of Arkansas for Medical Sciences (Site #208) Little Rock, Arkansas, United States
  • Profound Research LLC (Site #222) Carlsbad, California, United States
  • Collaborative Neuroscience Network - Los Alamitos- CenExel - PPDS (Site #217) Los Alamitos, California, United States
  • Keck Medicine of USC - USC Healthcare Center 2 (Site #221) Los Angeles, California, United States
View all 30 locations
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