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Clinical trial condition

Metastatic Colorectal Cancer

Explore clinical trials studying Metastatic Colorectal Cancer. Study availability and eligibility vary by location and protocol.

386 public trials 70 recruiting studies
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Metastatic Colorectal Cancer trial results

Active, Not Recruiting

A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

NCT05217446

Conditions
Colonic Diseases, Colonic Neoplasms, Colorectal Neoplasms, +11 more
Locations
  • Mayo Clinic Building - Phoenix Phoenix, Arizona, United States
  • Mayo Clinic Hospital Phoenix, Arizona, United States
  • Mayo Clinic Scottsdale, Arizona, United States
  • Mount Sinai Cancer Center Miami Beach, Florida, United States
View all 59 locations
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Active, Not Recruiting

A Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy as First-line Treatment in Subjects With RAS/BRAF Wild Metastatic Colorectal Cancer

NCT04854668

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +9 more
Locations
  • The People's Hospital of Chizhou Chizhou, Anhui, China
  • Fujian Medical University Union Hospital Fuzhou, Anhui, China
  • Anhui Provincial Hospital Hefei, Anhui, China
  • Anhui Cancer Hospital Hefei, Anhui, China
View all 92 locations
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Active, Not Recruiting

Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy.

NCT03869892

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +13 more
Locations
  • Centro de Oncología e Investigación de Buenos Aires COIBA Berazategui, Argentina
  • Hospital de Gastroenterología Dr. Carlos Borino Udaondo Oncology Unit Buenos Aires, Argentina
  • Fundación Favaloro Oncology Unit Buenos Aires, Argentina
  • Instituto Alexander Fleming Buenos Aires, Argentina
View all 190 locations
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Active, Not Recruiting

A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer

NCT05382442

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +9 more
Locations
  • Summit Therapeutics Research Site Los Angeles, California, United States
  • Summit Therapeutics Research Site Murrieta, California, United States
  • Summit Therapeutics Research Site Fairfax, Virginia, United States
  • The Sixth Hospital,Sun Yat-sen University Guanzhou, Guangdong, China
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Active, Not Recruiting

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

NCT04008030

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +9 more
Locations
  • Local Institution - 0059 Los Angeles, California, United States
  • Local Institution - 0130 Sacramento, California, United States
  • Local Institution - 0103 Denver, Colorado, United States
  • Local Institution - 0119 Arlington Heights, Illinois, United States
View all 157 locations
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Active, Not Recruiting

A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

NCT05608044

Conditions
Colonic Diseases, Colorectal Neoplasms, Diabetes Mellitus, Insulin-Dependent, 12, +11 more
Locations
  • HonorHealth Research Institute Scottsdale, Arizona, United States
  • City of Hope National Medical Center Duarte, California, United States
  • Keck School of Medicine of the University of Southern California Los Angeles, California, United States
  • Rocky Mountain Cancer Center - Aurora Aurora, Colorado, United States
View all 65 locations
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Active, Not Recruiting

Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine

NCT05201352

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +9 more
Locations
  • Centre Georges-François Leclerc Dijon, Bourgogne-Franche-Comté, France
  • CHU Dijon Dijon, Bourgogne-Franche-Comté, France
  • ICO Angers Angers, France
  • Institut Sainte Catherine Avignon, France
View all 14 locations
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Active, Not Recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

NCT04140526

Conditions
Adenocarcinoma, Adenoid Cystic Carcinoma, Adnexal Diseases, +94 more
Locations
  • Highlands Oncology Group Springdale, Arkansas, United States
  • University of California at Davis Davis, California, United States
  • The Oncology Institute of Hope and Innovation Downey, California, United States
  • City of Hope Cancer Center Duarte, California, United States
View all 37 locations
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