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Leptomeningeal Metastases

Clinical trial condition

Leptomeningeal Metastases

Explore clinical trials studying Leptomeningeal Metastases. Study availability and eligibility vary by location and protocol.

16 public trials 3 recruiting studies

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Leptomeningeal Metastases trial results

Recruiting

A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis

NCT05184816

Conditions: Central Nervous System Neoplasms, Disease Attributes, Leptomeningeal Metastases, +9 more
Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth (Limited Protocol Activities) Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen (Limited Protocol Activities) Montvale, New Jersey, United States

Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) Commack, New York, United States

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Recruiting

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

NCT06462092

Conditions: Breast Diseases, Breast Neoplasms, Central Nervous System Neoplasms, +9 more
Locations: The Affiliated Huizhou Hospital, Guangzhou Medical University Huizhou, Guangdong, China

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Recruiting

Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study

NCT06728865

Conditions: Brain Diseases, Brain Metastases, Brain Neoplasms, +20 more
Locations: Sun Yat-sen University Cancer Center Guangzhou, Guangdong, China

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Not Yet Recruiting

Phase 1 Study of WBRT or PCSI With REYOBIQ for Leptomeningeal Metastases

NCT07674693

Conditions: Central Nervous System Neoplasms, Leptomeningeal Metastases, Meningeal Carcinomatosis, +5 more
Locations: Not specified

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Not Yet Recruiting

High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

NCT06971406

Conditions: Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, +16 more
Locations: Not specified

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Not Yet Recruiting

Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal Metastases

NCT06861218

Conditions: Central Nervous System Neoplasms, Leptomeningeal Metastases, Meningeal Carcinomatosis, +5 more
Locations: Zhejiang Cancer Hospital Hangzhou, Zhejiang, China

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Not Yet Recruiting

Ivonescimab Combined With Chemotherapy for the Treatment of Leptomeningeal Metastases Failed to EGFR-TKIs

NCT06766591

Conditions: AK112, Central Nervous System Neoplasms, Chemotherapy, +9 more
Locations: Not specified

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Completed

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

NCT03719768

Conditions: Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, +9 more
Locations: H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States

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Completed

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

NCT04343573

Conditions: Central Nervous System Neoplasms, Leptomeningeal Metastases, Meningeal Carcinomatosis, +5 more
Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth (Limitedl protocol activities) Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen (Limited Protocol Activities) Montvale, New Jersey, United States

Memorial Sloan Kettering Commack (Limited Protocol Activities) Commack, New York, United States

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Completed

Intrathecal Pemetrexed for Leptomeningeal Metastasis

NCT05289908

Conditions: Central Nervous System Neoplasms, Leptomeningeal Metastases, Meningeal Carcinomatosis, +5 more
Locations: The First Hospital of Jilin University Changchun, Jilin, China

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Leptomeningeal Metastases

Leptomeningeal Metastases trial results

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