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Clinical trial condition

Leptomeningeal Disease

Explore clinical trials studying Leptomeningeal Disease. Study availability and eligibility vary by location and protocol.

13 public trials 7 recruiting studies
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Leptomeningeal Disease trial results

Recruiting

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

NCT02422641

Conditions
Breast Diseases, Breast Neoplasms, Central Nervous System Neoplasms, +9 more
Locations
  • Sidney Kimmel Comprehensive Cancer Center Baltimore, Maryland, United States
  • Siteman Cancer Center- Washington University School of Medicine in St. Louis St Louis, Missouri, United States
  • Comprehensive Cancer Center at Wake Forest University (CCCWFU) Winston-Salem, North Carolina, United States
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Recruiting

Non Interventional German Leptomeningeal Disease Register

NCT06146010

Conditions
Central Nervous System Neoplasms, Leptomeningeal Disease, Meningeal Neoplasms, +4 more
Locations
  • Universitätsklinikum Bonn Klinik und Poliklinik für Neurologie Bonn, Germany
  • Universitätsmedizin Mannheim Universitätsklinikum Mannheim GmbH Klinik für Neurologie Mannheim, Germany
  • Klinikum rechts der Isar | Technische Universität München; Klinik für Radioonkologie und Strahlentherapie München, Germany
  • Überörtliche Gemeinschaftspraxis für Hämatologie und Onkologie Münster, Germany
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Recruiting

Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease

NCT05800275

Conditions
Central Nervous System Neoplasms, HER2-Positive Metastatic Breast Cancer, Leptomeningeal Disease, +7 more
Locations
  • Institut Bergonié Bordeaux, France
  • Centre François Baclesse Caen, France
  • Centre Jean Perrin Clermont-Ferrand, France
  • Centre Georges-François Leclerc Dijon, France
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Recruiting

Intrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26)

NCT05112549

Conditions
Central Nervous System Neoplasms, Leptomeningeal Disease, Meningeal Neoplasms, +4 more
Locations
  • Universitätsklinikum Bonn Bonn, Germany
  • University Hospital Freiburg, Neurosurgery Freiburg im Breisgau, Germany
  • University Hospital Heidelberg, Neurooncology Heidelberg, Germany
  • SLK-Kliniken Heilbronn GmbH Klinik Heilbronn, Germany
View Trial Details
Not Yet Recruiting

B7-H3.CD28Z.CART in CNS Neoplasms

NCT07390539

Conditions
Atypical Teratoid/Rhabdoid Tumor, Brain Diseases, Brain Neoplasms, +30 more
Locations
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Dana-Farber Cancer Institute Boston, Massachusetts, United States
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