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High Risk Myelodysplastic Syndrome

Clinical trial condition

High Risk Myelodysplastic Syndrome

Explore clinical trials studying High Risk Myelodysplastic Syndrome. Study availability and eligibility vary by location and protocol.

19 public trials 5 recruiting studies

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High Risk Myelodysplastic Syndrome trial results

Completed

Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome

NCT03047993

Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia, Blasts 20-30 Percent of Bone Marrow Nucleated Cells, Blasts 20-30 Percent of Peripheral Blood White Cells, +18 more
Locations: M D Anderson Cancer Center Houston, Texas, United States

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Completed

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

NCT01823198

Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Erythroid Leukemia, Acute Megakaryoblastic Leukemia, +36 more
Locations: M D Anderson Cancer Center Houston, Texas, United States

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Completed

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

NCT03263637

Conditions: Acute Lymphocytic Leukemia, Acute Myeloid Leukemia, B-Cell Non-Hodgkin Lymphoma, +42 more
Locations: Research Site Aachen, Germany

Research Site Bonn, Germany

Research Site Göttingen, Germany

Research Site Heidelberg, Germany

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Completed

Pomalidomide After Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

NCT02029950

Conditions: Acute Myeloid Leukemia, Bone Marrow Diseases, Chronic Myelomonocytic Leukemia-2, +10 more
Locations: Yale University New Haven, Connecticut, United States

Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States

UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina, United States

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Completed

A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.

NCT01236144

Conditions: Acute Myeloid Leukaemia, Hematologic Diseases, Hemic and Lymphatic Diseases, +6 more
Locations: Aberdeen Royal Infirmary Aberdeen, United Kingdom

Belfast City Hospital Belfast, United Kingdom

Birmingham Heartlands Hospital Birmingham, United Kingdom

Addenbrooke's Hospital Cambridge, United Kingdom

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Active, Not Recruiting

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

NCT02530034

Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Blast Crisis, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, +31 more
Locations: Augusta University Augusta, Georgia, United States

Montefiore Medical Center, Albert Einstein College of Medicine The Bronx, New York, United States

M D Anderson Cancer Center Houston, Texas, United States

Huntsman Cancer Institute Salt Lake City, Utah, United States

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Active, Not Recruiting

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

NCT04128748

Conditions: Acute Myeloid Leukemia, Blasts More Than 10 Percent of Bone Marrow Nucleated Cells, Bone Marrow Diseases, +13 more
Locations: M D Anderson Cancer Center Houston, Texas, United States

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Active, Not Recruiting

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

NCT02861417

Conditions: Blood Protein Disorders, Bone Marrow Diseases, Cardiovascular Diseases, +46 more
Locations: M D Anderson Cancer Center Houston, Texas, United States

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Active, Not Recruiting

Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

NCT04262843

Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Bone Marrow Diseases, +16 more
Locations: City of Hope Medical Center Duarte, California, United States

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High Risk Myelodysplastic Syndrome

High Risk Myelodysplastic Syndrome trial results

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