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Clinical trial condition

gMG

Explore clinical trials studying gMG. Study availability and eligibility vary by location and protocol.

11 public trials 6 recruiting studies
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gMG trial results

Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

NCT07294170

Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, +15 more
Locations
  • Profound Research LLC - Carlsbad Carlsbad, California, United States
  • Visionary Investigators Network Miami, Florida, United States
  • University of South Florida Tampa, Florida, United States
  • Erlanger Health System Columbia, Maryland, United States
View all 29 locations
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Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

NCT07284420

Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, +15 more
Locations
  • Profound Research LLC - Carlsbad Carlsbad, California, United States
  • Visionary Investigators Network Miami, Florida, United States
  • University of South Florida Tampa, Florida, United States
  • Henry Ford Health Systems Detroit, Michigan, United States
View all 24 locations
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Recruiting

ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis

NCT07673627

Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, +14 more
Locations
  • Visionary Investigators Network Miami, Florida, United States
  • Erlanger Health System Chattanooga, Tennessee, United States
View Trial Details
Recruiting

A Study to Evaluate the Impact of Efgartigimod on Overall Disease Experience of People Suffering From Generalized Myasthenia Gravis (gMG) in Italy

NCT07595653

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis (gMG), +12 more
Locations
  • Ospedale Generale Regionale F. Miulli Acquaviva delle Fonti, Italy
  • Azienda Ospedaliero Universitaria delle Marche Ancona, Italy
  • A.O.U. Consorziale Policlinico Bari, Italy
  • ASST Papa Giovanni XXIII Bergamo, Italy
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Recruiting

A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab

NCT07221838

Conditions
Adrenal Gland Diseases, Adrenal Insufficiency, Autoimmune Diseases, +15 more
Locations
  • Research Site Chicago, Illinois, United States
  • Research Site Schaumburg, Illinois, United States
  • Research Site Neptune City, New Jersey, United States
  • Research Site Raleigh, North Carolina, United States
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Recruiting

PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+ Generalized Myasthenia Gravis

NCT06607627

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis, +12 more
Locations
  • Research Site Washington D.C., District of Columbia, United States
  • Research Site Norfolk, Virginia, United States
  • Research Site Joinville, Brazil
  • Research Site Salvador, Brazil
View all 13 locations
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Enrolling by Invitation

Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis

NCT05374590

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis, +12 more
Locations
  • Ann and Robert H Lurie Children's Hospital of Chicago - Main Hospital Chicago, Illinois, United States
  • Atrium Health Neurology Specialty Care Charlotte, North Carolina, United States
  • University of Virginia (UVA) Health - Developmental Pediatrics Clinic Charlottesville, Virginia, United States
  • Universitair Ziekenhuis Antwerpen Edegem, Belgium
View all 16 locations
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Completed

An Open-label Study to Investigate the Clinical Efficacy of Different Dosing Regimens of Efgartigimod IV in Patients With Generalized Myasthenia Gravis

NCT04980495

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis, +13 more
Locations
  • Investigator Site 10 - US0010007 Carlsbad, California, United States
  • Investigator Site 7 - US0010001 Orange, California, United States
  • Investigator Site 9 - 0010006 Boca Raton, Florida, United States
  • Investigator Site 15 - US0010014 Coral Springs, Florida, United States
View all 39 locations
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Active, Not Recruiting

Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis

NCT05644561

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis, +12 more
Locations
  • Research Site Los Angeles, California, United States
  • Research Site Boston, Massachusetts, United States
  • Research Site Chapel Hill, North Carolina, United States
  • Research Site Philadelphia, Pennsylvania, United States
View Trial Details

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