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Clinical trial condition

Digestive System Diseases

Explore clinical trials studying Digestive System Diseases. Study availability and eligibility vary by location and protocol.

31,800 public trials 5,675 recruiting studies
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Digestive System Diseases trial results

Recruiting

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

NCT06780111

Conditions
Carcinoma, Carcinoma, Squamous Cell, Digestive System Diseases, +12 more
Locations
  • UPMC Hillman Cancer Center ( Site 1904) Pittsburgh, Pennsylvania, United States
  • Liga Norte Riograndense Contra o Cancer ( Site 1301) Natal, Rio Grande do Norte, Brazil
  • Hospital Nossa Senhora da Conceicao ( Site 1300) Porto Alegre, Rio Grande do Sul, Brazil
  • Clínica Puerto Montt ( Site 1406) Port Montt, Los Lagos Region, Chile
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Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

NCT04924075

Conditions
Abnormalities, Multiple, Adenoma, Adenoma, Islet Cell, +31 more
Locations
  • Cedars-Sinai Medical Center ( Site 0110) Los Angeles, California, United States
  • Northwestern University - Robert H. Lurie Comprehensive Cancer Center ( Site 0130) Chicago, Illinois, United States
  • Northwestern Medicine Cancer Center - Warrenville ( Site 0134) Warrenville, Illinois, United States
  • University of Iowa ( Site 0104) Iowa City, Iowa, United States
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Recruiting

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

NCT05673148

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +11 more
Locations
  • Kingman Regional Medical Center Kingman, Arizona, United States
  • Mayo Clinic Hospital in Arizona Phoenix, Arizona, United States
  • Tower Cancer Research Foundation Beverly Hills, California, United States
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California, United States
View all 187 locations
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Recruiting

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

NCT07288138

Conditions
Digestive System Diseases, Fatty Liver, Liver Diseases, +2 more
Locations
  • Arizona Liver Health Chandler, Arizona, United States
  • Arizona Liver Health - Peoria Peoria, Arizona, United States
  • Adobe Clinical Research, LLC Tucson, Arizona, United States
  • Arizona Liver Health - Tucson Tucson, Arizona, United States
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Recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

NCT06445972

Conditions
Digestive System Diseases, Digestive System Neoplasms, Esophageal Cancer, +10 more
Locations
  • University of Arizona Cancer Center-University of Arizona Cancer Center ( Site 8927) Tucson, Arizona, United States
  • UCLA Hematology/Oncology - Santa Monica ( Site 8905) Los Angeles, California, United States
  • Norton Cancer Institute - Downtown ( Site 8900) Louisville, Kentucky, United States
  • The Cancer and Hematology Centers ( Site 8912) Grand Rapids, Michigan, United States
View all 46 locations
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Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT06252649

Conditions
Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases, +9 more
Locations
  • Ironwood Cancer and Research Centers Scottsdale Chandler, Arizona, United States
  • Providence Saint Jude Medical Center Fullerton, California, United States
  • City of Hope National Medical Center Long Beach, California, United States
  • Cancer and Blood Research Center, LLC Los Alamitos, California, United States
View all 291 locations
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Recruiting

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

NCT06760819

Conditions
Adnexal Diseases, Advanced Solid Tumors, Biliary Tract Diseases, +53 more
Locations
  • UAB O'Neal Comprehensive Cancer Center - The Kirklin Clinic of UAB Hospital Birmingham, Alabama, United States
  • City of Hope - Duarte Cancer Center Duarte, California, United States
  • Florida Cancer Specialists & Research Institute - Fort Myers Cancer Center - Gladiolus Fort Myers, Florida, United States
  • Dana-Farber Cancer Institute - Oncology Department Boston, Massachusetts, United States
View all 54 locations
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Recruiting

Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

NCT05687123

Conditions
Adenoma, Adenoma, Islet Cell, Digestive System Diseases, +14 more
Locations
  • City of Hope Comprehensive Cancer Center Duarte, California, United States
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California, United States
  • UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California, United States
  • Memorial Hospital East Shiloh, Illinois, United States
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Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

NCT07644559

Conditions
Digestive System Diseases, Digestive System Neoplasms, Endocrine Gland Neoplasms, +7 more
Locations
  • START- Los Angeles Los Angeles, California, United States
  • Valkyrie Clinical Trials Los Angeles, California, United States
  • Moffitt Cancer Center Tampa, Florida, United States
  • Johns Hopkins University Baltimore, Maryland, United States
View all 29 locations
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