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Clinical trial condition

Depressive Disorder, Major

Explore clinical trials studying Depressive Disorder, Major. Study availability and eligibility vary by location and protocol.

283 public trials 31 recruiting studies
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Depressive Disorder, Major trial results

Completed

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

NCT03039192

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • UAB Department of Psychiatry and Behavioral Neurobiology Birmingham, Alabama, United States
  • Metropolitan Neuro Behavioral Institute Chandler, Arizona, United States
  • Collaborative NeuroScience Network Garden Grove, California, United States
  • Yale University New Haven, Connecticut, United States
View all 56 locations
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Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

NCT03185819

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • Institute of Living/ Hartford Hospital Hartford, Connecticut, United States
  • Yale University New Haven, Connecticut, United States
  • Atlanta Behavioral Research, LLC Atlanta, Georgia, United States
  • Rush University Medical Center Chicago, Illinois, United States
View all 51 locations
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Completed

A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

NCT03321526

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • NoesisPharma Research Phoenix, Arizona, United States
  • Clinical Research Consortium Arizona Tempe, Arizona, United States
  • Woodland Research Northwest Rogers, Arkansas, United States
  • Collaborative NeuroScience Network Garden Grove, California, United States
View all 50 locations
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Completed

54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

NCT03097133

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • University of California San Diego/Psychiatry San Diego, California, United States
  • Sharp Mesa Vista Hospital San Diego, California, United States
  • University of Conneticut School of Medicine Farmington, Connecticut, United States
  • University of Miami Health System Miami, Florida, United States
View all 61 locations
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Completed

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder

NCT04338321

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • Fundacion para el Estudio y Tratamiento de las Enfermedades Mentales Buenos Aires, Argentina
  • FunDaMos Buenos Aires, Argentina
  • CEN Consultorios Especializados en Neurociencias Córdoba, Argentina
  • Fundacion Lennox Córdoba, Argentina
View all 171 locations
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Completed

A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

NCT03227224

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • California Pharmaceutical Research Institute, Inc. Anaheim, California, United States
  • Catalina Research Institute Chino, California, United States
  • Synergy Clinical Research Center Of Escondido Lemon Grove, California, United States
  • Asclepes Research Panorama City, California, United States
View all 101 locations
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Completed

A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of Depression

NCT03559192

Conditions
Depressive Disorder, Depressive Disorder, Major, Mental Disorders, +1 more
Locations
  • Noble Clinical Research Tucson, Arizona, United States
  • Preferred Research Partners Little Rock, Arkansas, United States
  • Behavioral Research Specialists LLC Glendale, California, United States
  • NRC Research Institute Orange, California, United States
View all 53 locations
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