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OpenTrials

Clinical trial condition

Demyelinating Diseases

Explore clinical trials studying Demyelinating Diseases. Study availability and eligibility vary by location and protocol.

2,934 public trials 459 recruiting studies
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Demyelinating Diseases trial results

Completed

A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration

NCT03689972

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +5 more
Locations
  • North Central Neurology Associates, P.C. Cullman, Alabama, United States
  • Alabama Neurology Associates Homewood, Alabama, United States
  • UCI MIND Irvine, California, United States
  • UC San Diego Movement Disorder Center La Jolla, California, United States
View all 107 locations
View Trial Details
Completed

An Observational Biomarker Study in Multiple Sclerosis (MS) Patients

NCT05663853

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Chronic Disease, +12 more
Locations
  • The Johns Hopkins University Baltimore, Maryland, United States
  • MedStar Health Chevy Chase, Maryland, United States
  • Corinne Goldsmith Dickinson Center for MS New York, United States
  • Mellen Center Cleveland, Ohio, United States
View Trial Details
Completed

Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)

NCT01665144

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Chronic Disease, +10 more
Locations
  • Novartis Investigative Site Phoenix, Arizona, United States
  • Novartis Investigative Site Berkeley, California, United States
  • Novartis Investigative Site Los Angeles, California, United States
  • Novartis Investigative Site Oceanside, California, United States
View all 290 locations
View Trial Details
Completed

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

NCT02688985

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Chronic Disease, +11 more
Locations
  • Stanford University Palo Alto, California, United States
  • University of California at San Francisco San Francisco, California, United States
  • University Of Colorado Aurora, Colorado, United States
  • Yale University School of Medicine ; Pulmonary & Critical Care New Haven, Connecticut, United States
View all 17 locations
View Trial Details
Completed

Mechanistic Study of Ocrevus

NCT04459988

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • University of Michigan Ann Arbor, Michigan, United States
View Trial Details

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