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Clinical trial condition

Demyelinating Autoimmune Diseases, CNS

Explore clinical trials studying Demyelinating Autoimmune Diseases, CNS. Study availability and eligibility vary by location and protocol.

2,728 public trials 404 recruiting studies
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Demyelinating Autoimmune Diseases, CNS trial results

Active, Not Recruiting

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

NCT04548999

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Chronic Disease, +9 more
Locations
  • Alabama Neurology Associates Homewood, Alabama, United States
  • 21st Century Neurology Phoenix, Arizona, United States
  • University of California Irvine Irvine, California, United States
  • Stanford University Medical Center Stanford, California, United States
View all 147 locations
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Active, Not Recruiting

A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis

NCT03523858

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Chronic Disease, +10 more
Locations
  • MS Center of California Laguna Hills, California, United States
  • SC3 Research Group, Inc Pasadena, California, United States
  • University of California San Francisco San Francisco, California, United States
  • University of South Florida Tampa, Florida, United States
View all 120 locations
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Active, Not Recruiting

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT06141473

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • University of Alabama at Birmingham- Site Number : 8401135 Birmingham, Alabama, United States
  • North Central Neurology Associates- Site Number : 8401100 Cullman, Alabama, United States
  • Alabama Neurology Associates- Site Number : 8400115 Homewood, Alabama, United States
  • St. Joseph's Hospital and Medical Center- Site Number : 8401139 Phoenix, Arizona, United States
View all 382 locations
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Active, Not Recruiting

Validation and Standardization of Paramagnetic Rim Lesion (PRL) Identification in Multiple Sclerosis Across MAGNIMS Centers

NCT07705581

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • Medical University Graz Graz, Austria
  • Medical University of Vienna Vienna, Austria
  • Charles University and General University Hospital Prague, Czechia
  • Danish Research Centre for Magnetic Resonance Copenhagen, Denmark
View all 15 locations
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Active, Not Recruiting

A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)

NCT05123703

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +6 more
Locations
  • UC San Diego La Jolla, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Children's National Hospital Washington D.C., District of Columbia, United States
  • Johns Hopkins Medicine Baltimore, Maryland, United States
View all 71 locations
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Active, Not Recruiting

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in Participants With Multiple Sclerosis

NCT07008378

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • UCI Sue & Bill Gross Stem Cell Research Center Irvine, California, United States
  • UCSD Altman Clinical and Translational Research Institute La Jolla, California, United States
  • Washington University School of Medicine St Louis, Missouri, United States
  • Rutgers University- Robert Wood Johnson Medical School New Brunswick, New Jersey, United States
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Active, Not Recruiting

OFSEP Very High Definition Cohort

NCT05622643

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • CHU de Lyon Lyon, France
  • CHU de Nancy Nancy, France
  • CHU de Nîmes Nîmes, France
  • CHU de Rennes Rennes, France
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Active, Not Recruiting

A Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of RPH-035 and Ocrevus® in Patients With Relapsing-remitting or Secondary Progressive Multiple Sclerosis With Exacerbations

NCT07597668

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • State Autonomous Healthcare Institution Regional Clinical Hospital No. 3 Chelyabinsk, Russia
  • Kazan State Medical Academy, branch of the Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuing Professional Education Kazan', Russia
  • State Autonomous Healthcare Institution "Interregional Clinical and Diagnostic Center" Kazan', Russia
  • Kirov Regional State Clinical Budgetary Healthcare Institution "Center for Cardiology and Neurology" Kirov, Russia
View all 23 locations
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Active, Not Recruiting

OFSEP High Definition Cohort

NCT03603457

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS, +4 more
Locations
  • CHU de Besançon Besançon, France
  • CHU de Bordeaux Bordeaux, France
  • CHU de Caen Caen, France
  • CHU de Clermont-Ferrand Clermont-Ferrand, France
View all 25 locations
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