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OpenTrials

Clinical trial condition

Cholestasis

Explore clinical trials studying Cholestasis. Study availability and eligibility vary by location and protocol.

174 public trials 37 recruiting studies
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Cholestasis trial results

Completed

Study to Assess Safety & Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodiol.

NCT03226067

Conditions
Bile Duct Diseases, Biliary Tract Diseases, Cholestasis, +9 more
Locations
  • Mayo Clinic Phoenix, Arizona, United States
  • University California Davis Sacramento, California, United States
  • Ventura Clinical Trials Ventura, California, United States
  • Yale School of Medicine New Haven, Connecticut, United States
View all 61 locations
View Trial Details
Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

NCT02047318

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Birmingham Children's Hospital Birmingham, West Midlands, United Kingdom
  • Leeds Teaching Hospital NHS Trust Leeds, West Yorkshire, United Kingdom
  • Kings College Hospital London, United Kingdom
View Trial Details
Completed

Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS)

NCT02160782

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Children's Hospital Westmead Westmead, New South Wales, Australia
  • The Royal Children's Hospital Melbourne Parkville, Victoria, Australia
  • Cliniques Universitaires Saint-Luc Brussels, Belgium
  • Hopital Femme Mere Enfant De Lyon Bron, France
View Trial Details
Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome

NCT02117713

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of California at San Francisco Children's Hospital San Francisco, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Riley Hospital for Children Indianapolis, Indiana, United States
View Trial Details
Completed

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

NCT00570765

Conditions
Bile Duct Diseases, Biliary Tract Diseases, Cholestasis, +8 more
Locations
  • Henry Ford Detroit, Michigan, United States
  • Baylor College of Medicine Houston, Texas, United States
  • Virginia Commonwealth University Richmond, Virginia, United States
  • Virginia Mason Medical Center Seattle, Washington, United States
View all 21 locations
View Trial Details
Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis

NCT03394924

Conditions
Bile Duct Diseases, Biliary Tract Diseases, Cholestasis, +9 more
Locations
  • Digestive Health Specialists of the Southeast Dothan, Alabama, United States
  • Arkansas Diagnostic Center Little Rock, Arkansas, United States
  • Texas Clinical Research Institute Little Rock, Arkansas, United States
  • Southern California Research Center Coronado, California, United States
View all 86 locations
View Trial Details
Completed

Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis

NCT01473524

Conditions
Bile Duct Diseases, Biliary Tract Diseases, Cholestasis, +9 more
Locations
  • UC Davis Medical Center Sacramento, California, United States
  • Scripps Clinic San Diego, California, United States
  • University of Colorado, Denver Aurora, Colorado, United States
  • University of Chicago Chicago, Illinois, United States
View all 59 locations
View Trial Details
Completed

A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients

NCT02516605

Conditions
Bile Duct Diseases, Biliary Tract Diseases, Cholestasis, +9 more
Locations
  • Novartis Investigative Site Rialto, California, United States
  • Novartis Investigative Site Miami, Florida, United States
  • Novartis Investigative Site Atlanta, Georgia, United States
  • Novartis Investigative Site Marietta, Georgia, United States
View all 28 locations
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