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A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)
NCT06275620
- Conditions
- Eye Diseases, Eye Diseases, Hereditary, Retinal Degeneration, +2 more
- Locations
-
- University of Florida Jacksonville, Florida, United States
- Bascom Palmer Eye Institute Miami, Florida, United States
- Boston Children's Hospital Boston, Massachusetts, United States
- Cincinnati Eye Institute Cincinnati, Ohio, United States
NCT03584165
- Conditions
- Choroid Diseases, Choroideremia, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +6 more
- Locations
-
- UCLA - Jules Stein Eye Institute Los Angeles, California, United States
- Vitreo Retinal Associates PA - The Millennium Center Gainesville, Florida, United States
- University of Miami Miami, Florida, United States
- Johns Hopkins Hospital Baltimore, Maryland, United States
NCT04671433
- Conditions
- X-Linked Retinitis Pigmentosa
- Locations
-
- Shiley Eye Institute Jacobs Retina Center La Jolla, California, United States
- Childrens Hospital Los Angeles, California, United States
- Stanford Health Care Palo Alto, California, United States
- VitreoRetinal Associates, PA Gainesville, Florida, United States
NCT04312672
- Conditions
- X-Linked Retinitis Pigmentosa
- Locations
-
- Massachusetts Eye and Ear Infirmary Boston, Massachusetts, United States
- Univ of Michigan Medical Center Ann Arbor, Michigan, United States
- University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States
- Leeds Teaching Hospitals NHS Trust Leeds, United Kingdom
Completed
Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)
NCT03252847
- Conditions
- X-Linked Retinitis Pigmentosa
- Locations
-
- Massachusetts Eye and Ear Institute Boston, Massachusetts, United States
- Kellogg Eye Center Ann Arbor, Michigan, United States
- UPMC Eye Center Pittsburgh, Pennsylvania, United States
- Leeds Teaching Hospitals NHS Trust Leeds, United Kingdom
NCT03116113
- Conditions
- Cone-Rod Dystrophy, X-Linked, Type 1, X-Linked Retinitis Pigmentosa
- Locations
-
- Research Site Gainesville, Florida, United States
- Research Site Miami, Florida, United States
- Research Site Portland, Oregon, United States
- Research Site Philadelphia, Pennsylvania, United States
NCT04926129
- Conditions
- Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, +2 more
- Locations
-
- Research Site Phoenix, Arizona, United States
- Research Site Los Angeles, California, United States
- Research Site San Francisco, California, United States
- Research Site Miami, Florida, United States
NCT03314207
- Conditions
- Eye Diseases, Eye Diseases, Hereditary, Retinal Degeneration, +2 more
- Locations
-
- Duke Eye Center, Duke University Medical Center Durham, North Carolina, United States
- Casey Eye Institute, Oregon Health and Sciences University Portland, Oregon, United States
- Retina Foundation of the Southwest Dallas, Texas, United States
Active, Not Recruiting
Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
NCT04794101
- Conditions
- X-Linked Retinitis Pigmentosa
- Locations
-
- Shiley Eye Institute Jacobs Retina Center La Jolla, California, United States
- Childrens Hospital Los Angeles Los Angeles, California, United States
- Stanford Health Care Palo Alto, California, United States
- VitreoRetinal Associates, PA Gainesville, Florida, United States
Active, Not Recruiting
A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)
NCT06646289
- Conditions
- X-Linked Retinitis Pigmentosa
- Locations
-
- Massachusetts Eye and Ear Infirmary Boston, Massachusetts, United States
- University of Michigan Kellogg Eye Center Ann Arbor, Michigan, United States
- Moorfields Eye Hospital London, United Kingdom
Active, Not Recruiting
A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP
NCT04850118
- Conditions
- Eye Diseases, Eye Diseases, Hereditary, Retinal Degeneration, +2 more
- Locations
-
- Retina Macula Institute of Arizona Scottsdale, Arizona, United States
- Children's Hospital Los Angeles Los Angeles, California, United States
- University of Florida Health Jacksonville, Department of Ophthalmology Jacksonville, Florida, United States
- Bascom Palmer Eye Institute- University of Miami Miami, Florida, United States
Active, Not Recruiting
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
NCT04517149
- Conditions
- X-Linked Retinitis Pigmentosa
- Locations
-
- University of Colorado Aurora, Colorado, United States
- Vitreo Retinal Associates Gainesville, Florida, United States
- University of Michigan Kellogg Eye Center Ann Arbor, Michigan, United States
- Columbia University Medical Center/Edward Harkness Eye Institute New York, United States
Active, Not Recruiting
A Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)
NCT06333249
- Conditions
- Eye Diseases, Eye Diseases, Hereditary, Retinal Degeneration, +2 more
- Locations
-
- University of Florida Jacksonville, Florida, United States
- Boston Children's Hosptial Boston, Massachusetts, United States
- Cincinnati Eye Institute Cincinnati, Ohio, United States
- Cleveland Clinic Cleveland, Ohio, United States
Active, Not Recruiting
Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations
NCT03316560
- Conditions
- Eye Diseases, Eye Diseases, Hereditary, Retinal Degeneration, +2 more
- Locations
-
- Duke University Durham, North Carolina, United States
- Cincinnati Eye Institute Cincinnati, Ohio, United States
- Casey Eye Institute Portland, Oregon, United States
- Retina Foundation of the Southwest Dallas, Texas, United States