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Recruiting

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

NCT07469891

Conditions
Bone Marrow Diseases, Bone Marrow Neoplasms, Hematologic Diseases, +13 more
Locations
  • Colorado Blood Cancer Institute Denver, Colorado, United States
  • BRCR Global - Coral Springs Coral Springs, Florida, United States
  • START Midwest, LLC Grand Rapids, Michigan, United States
  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Trials Office Philadelphia, Pennsylvania, United States
View Trial Details
Recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

NCT06343805

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +7 more
Locations
  • Stanford Cancer Institute Palo Alto, California, United States
  • Moffitt Cancer Cancer Center Tampa, Florida, United States
  • University of Kansas Medical Center Kansas City, Kansas, United States
  • Massachusetts General Hospital Boston, Massachusetts, United States
View all 21 locations
View Trial Details
Recruiting

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

NCT06351631

Conditions
Blood Coagulation Disorders, Blood Platelet Disorders, Bone Marrow Diseases, +15 more
Locations
  • University of Michigan ( Site 6000) Ann Arbor, Michigan, United States
  • DUHS Duke Blood Cancer Center ( Site 6005) Durham, North Carolina, United States
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 6007) Columbus, Ohio, United States
  • UPMC Hillman Cancer Center ( Site 6004) Pittsburgh, Pennsylvania, United States
View all 21 locations
View Trial Details
Completed

A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)

NCT04173494

Conditions
Anemia, Bone Marrow Diseases, Hematologic Diseases, +5 more
Locations
  • Mayo Clinic Hospital - Phoenix Phoenix, Arizona, United States
  • Irvine Center for Clinical Research Irvine, California, United States
  • Norris Comprehensive Cancer Center Los Angeles, California, United States
  • American Institute of Research - Whittier Whittier, California, United States
View all 167 locations
View Trial Details
Completed

Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia

NCT02124746

Conditions
Blood Coagulation Disorders, Blood Platelet Disorders, Bone Marrow Diseases, +15 more
Locations
  • Scottsdale, Arizona, United States
  • Orange, California, United States
  • Stanford, California, United States
  • Whittier, California, United States
View all 22 locations
View Trial Details
Completed

Phase 2 Study: An Open-Label, Randomized, Phase 2 Dose-Finding Study of Pacritinib in Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post- Essential Thrombocythemia Myelofibrosis Previously Treated With Ruxolitinib

NCT04884191

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +4 more
Locations
  • Mayo Clinic Hospital Phoenix, Arizona, United States
  • City of Hope Duarte, California, United States
  • USC Norris Comprehensive Cancer Center Los Angeles, California, United States
  • UCLA Jonsson Comprehensive Cancer Center Los Angeles, California, United States
View all 62 locations
View Trial Details
Completed

Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF

NCT01423851

Conditions
Blood Coagulation Disorders, Blood Platelet Disorders, Bone Marrow Diseases, +14 more
Locations
  • Mayo Clinic Scottsdale Recruiting Scottsdale, Arizona, United States
  • UC San Diego Moores Cancer Center San Diego, California, United States
  • Mayo Clinic, Jacksonville Jacksonville, Florida, United States
  • Northwestern University Chicago, Illinois, United States
View Trial Details
Completed

Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

NCT01236638

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +4 more
Locations
  • Stanford Cancer Center Stanford, California, United States
  • Dana-Farber Cancer Institute Boston, Massachusetts, United States
  • Mayo Clinic Rochester, Minnesota, United States
  • The Royal Melbourne Hospital Parkville, Victoria, Australia
View Trial Details
Completed

Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

NCT00935987

Conditions
Bone Marrow Diseases, Hematologic Diseases, Hemic and Lymphatic Diseases, +4 more
Locations
  • Stanford Cancer Center Stanford, California, United States
  • Dana-Farber Cancer Institute Boston, Massachusetts, United States
  • Mayo Clinic Rochester, Minnesota, United States
  • The Royal Melbourne Hospital Parkville, Victoria, Australia
View Trial Details