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Completed

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

NCT01419028

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +16 more
Locations
  • Cedars-Sinai Medical Center Los Angeles, California, United States
  • Indiana University school of medicine Indianapolis, Indiana, United States
  • Shriners Hospital for Children St Louis, Missouri, United States
  • Oregon Health & Science University Portland, Oregon, United States
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Completed

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

NCT00744042

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +16 more
Locations
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Alfred I. duPont Hospital for Children Wilmington, Delaware, United States
  • St. John's Hospital Springfield, Missouri, United States
  • University of Nebraska Medical Center, Munroe-Meyer Institute Omaha, Nebraska, United States
View Trial Details
Completed

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

NCT00739505

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +16 more
Locations
  • Barnes Jewish Hospital- Washington University School of Medicine St Louis, Missouri, United States
  • Duke University Medical Center Durham, North Carolina, United States
  • Department of Pediatrics & Child Health, Health Sciences Centre Winnipeg, University of Manitoba Winnipeg, Manitoba, Canada
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Completed

Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)

NCT01205152

Conditions
Avitaminosis, Bone Diseases, Bone Diseases, Metabolic, +15 more
Locations
  • Alfred I. DuPont Hospital for Children Wilmington, Delaware, United States
  • St. John's Medical Research Institute Springfield, Missouri, United States
  • University of Nebraska Medical Center Omaha, Nebraska, United States
  • Vanderbilt University Medical Center Nashville, Tennessee, United States
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