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Recruiting
Stem Cell Ophthalmology Treatment Study II
NCT03011541
- Conditions
- Abnormalities, Multiple, Age-Related Macular Degeneration, Autoimmune Diseases, +75 more
- Locations
-
- MD Stem Cells Westport, Connecticut, United States
- MD Stem Cells Coral Springs, Florida, United States
- MD Stem Cells Kobinia Med Vienna, Austria
- The Saudi-German Hospital Dubai, United Arab Emirates
Recruiting
Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)
NCT06891443
- Conditions
- Blindness, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +28 more
- Locations
-
- UCSF Wayne and Gladys Valley Center for Vision San Francisco, California, United States
- University of Miami - Bascom Palmer Eye Institute Miami, Florida, United States
- University of Iowa Iowa City, Iowa, United States
- University of Minnesota Medical School Minneapolis, Minnesota, United States
Recruiting
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
- Conditions
- Abnormalities, Multiple, Acid-Base Imbalance, Acidosis, +86 more
- Locations
-
- University of California San Diego San Diego, California, United States
- Lucile Packard Children's Hospital Stanford, California, United States
- Children's Hospital of Colorado Aurora, Colorado, United States
- Children's National Medical Center Washington D.C., District of Columbia, United States
NCT03475173
- Conditions
- Acute Zonal Occult Outer Retinopathy, Acute zonal occult outer retinopathy, Arterial Occlusive Diseases, +31 more
- Locations
-
- University of Iowa Department of Ophthalmology Iowa City, Iowa, United States
NCT03293524
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Doheny Eye Center UCLA Pasadena Pasadena, California, United States
- University of Colorado Health Eye Center Aurora, Colorado, United States
- Emory Healthcare - The Emory Clinic Atlanta, Georgia, United States
- Massachusetts Eye and Ear Infirmary Boston, Massachusetts, United States
Completed
REALITY LHON Registry
NCT03295071
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Doheny Eye Center UCLA Pasadena Pasadena, California, United States
- Emory University Hospital Atlanta, Georgia, United States
- Massachusetts Eye and Ear Infirmary Boston, Massachusetts, United States
- Wills Eye Institute Philadelphia, Pennsylvania, United States
Completed
RESCUE and REVERSE Long-term Follow-up
NCT03406104
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Doheny Eye Center UCLA Pasadena, California, United States
- Emory University Hospital Atlanta, Georgia, United States
- Wills Eye Institute Philadelphia, Pennsylvania, United States
- CHNO Les Quinze Vingts Paris, France
NCT02652780
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Doheny Eye Center, University of California, Los Angeles Los Angeles, California, United States
- Department of Ophthalmology, Emory University School of Medicine Atlanta, Georgia, United States
- Neuro Ophthalmologic Associates, Wills Eye Hospital, Thomas Jefferson University Philadelphia, Pennsylvania, United States
- Centre National Hospitalier d'Ophtalmologie des Quinze-Vingt Paris, France
NCT02652767
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Doheny Eye Center, University of California, Los Angeles Los Angeles, California, United States
- Department of Ophthalmology, Emory University School of Medicine Atlanta, Georgia, United States
- Neuro Ophthalmologic Associates, Wills Eye Hospital, Thomas Jefferson University Philadelphia, Pennsylvania, United States
- Centre National Hospitalier d'Ophtalmologie des Quinze-VingtCentre National Hospitalier d'Ophtalmologie des Quinze-Vingt Paris, France
NCT02161380
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Bascom Palmer Eye Institute, University of Miami Miami, Florida, United States
NCT02023866
- Conditions
- Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +40 more
- Locations
-
- University of California at San Diego (UCSD) San Diego, California, United States
- Stanford University Stanford, California, United States
- Akron Children's Hospital Akron, Ohio, United States
- Baylor College of Medicine Houston, Texas, United States
NCT03140969
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +14 more
- Locations
-
- University of Iowa Iowa City, Iowa, United States
- Scheie Eye Institute, University of Pennsylvania Philadelphia, Pennsylvania, United States
- Ghent University Hospital and Ghent University Ghent, Belgium
NCT02774005
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Retinal Consultants of Arizona Phoenix, Arizona, United States
- Palo Alto Medical Foundation Palo Alto, California, United States
- Stanford Byers Eye Institute Stanford, California, United States
- University of Colorado Health Eye Center Aurora, Colorado, United States
NCT02693119
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Doheny Eye Center Pasadena, California, United States
NCT01064505
- Conditions
- Cardiovascular Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, +19 more
- Locations
-
- Retinal Consultants of Arizona Phoenix, Arizona, United States
- Retina-Vitreous Associates Medical Group Beverly Hills, California, United States
- Jules Stein Eye Institute, University of California, Los Angeles Los Angeles, California, United States
- Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus, University of Colorado Aurora, Colorado, United States
Active, Not Recruiting
Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations
NCT05293626
- Conditions
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cranial Nerve Diseases, Eye Diseases, +13 more
- Locations
-
- Stanford Byers Eye Institute Palo Alto, California, United States
- University of Colorado Health Eye Center Aurora, Colorado, United States
- Wills Eye Hospital, Neuro Ophthalmology Department Philadelphia, Pennsylvania, United States
Active, Not Recruiting
A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)
NCT03913143
- Conditions
- Blindness, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +26 more
- Locations
-
- University of Iowa Iowa City, Iowa, United States
- Universitair Ziekenhuis Gent (UZ) Ghent, Belgium
- INRET Clínica/ Santa Casa de Misericórdia de Belo Horizonte Belo Horizonte, Minas Gerais, Brazil
- Federal University of São Paulo - Hospital São Paulo (UNIFESP-HSP) São Paulo, Brazil