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Recruiting

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

NCT06451757

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +22 more
Locations
  • Massachusetts General Hospital Boston, Massachusetts, United States
  • Cleveland Clinic Neurological Institute Mellen Center Cleveland, Ohio, United States
  • The University of Texas Health Science Center at Houston Houston, Texas, United States
  • Rigshospitalet, University of Copenhagen Kopenhagen, Region Sjælland, Denmark
View Trial Details
Recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

NCT01694940

Conditions
Abnormalities, Multiple, Acid-Base Imbalance, Acidosis, +86 more
Locations
  • University of California San Diego San Diego, California, United States
  • Lucile Packard Children's Hospital Stanford, California, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
  • Children's National Medical Center Washington D.C., District of Columbia, United States
View all 17 locations
View Trial Details
Completed

A Phase 2b Study of Zagociguat in Patients With MELAS

NCT06402123

Conditions
Acid-Base Imbalance, Acidosis, Acidosis, Lactic, +23 more
Locations
  • UC San Diego - Altman Clinical and Translational Research Institute La Jolla, California, United States
  • Children's Hospital of Colorado Aurora, Colorado, United States
  • Rare Disease Research Atlanta, Georgia, United States
  • Massachusetts General Hospital Boston, Massachusetts, United States
View all 20 locations
View Trial Details
Completed

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION)

NCT05972954

Conditions
Acid-Base Imbalance, Acidosis, Acidosis, Lactic, +44 more
Locations
  • Universitätsklinikum Bonn, Sektion Neuromuskuläre Erkrankungen, Klinik und Poliklinik für Neurologie, Venusberg-Campus 1, Gebäude 80, NPP Bonn, Germany
  • Medizinisch Fakultät der Martin-Luther-Universität Halle-Wittenberg Universitätsklinik und Poliklinik für Neurologie Universitätsklinikum , Ernst-Grube-Str. 40 Halle, Germany
  • Friedrich-Baur-Institut an der Neurologischen Klinik und Poliklinik, Klinikum der Universität München, Ludwig-Maximilians-Universität (LMU Klinikum), Ziemssenstr. 1a Munich, Germany
  • IRCCS Institute of Neurological Science of Bologna, University of Bologna, Department of Biomedical and Neuromotor Science (DIBINEM), Ospedale Bellaria Via Altura, 3 Bologna, Italy
View Trial Details
Completed

A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease

NCT05218655

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Brain Diseases, +36 more
Locations
  • University of California, San Diego Altman Clinical and Translational Research Institute La Jolla, California, United States
  • Stanford University Stanford, California, United States
  • Yale Medicine New Haven, Connecticut, United States
  • Children's National Washington D.C., District of Columbia, United States
View all 26 locations
View Trial Details
Completed

The KHENEREXT Study

NCT04604548

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +35 more
Locations
  • Rigshospitalet, University of Copenhagen Copenhagen, Denmark
  • Klinikum der Universität München Friedrich-Baur-Institut München, Germany
  • Radboud University Medical Center Nijmegen, Netherlands
  • Institute for Ageing and Health Newcastle University Newcastle upon Tyne, United Kingdom
View Trial Details
Completed

The KHENERGYZE Study

NCT04165239

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +19 more
Locations
  • Rigshospitalet, University of Copenhagen Copenhagen, Denmark
  • Friedrich-Baur Institut München, Bavaria, Germany
  • Radboud University Medical Center Nijmegen, Netherlands
  • Institute for Ageing and Health Newcastle University Newcastle upon Tyne, United Kingdom
View Trial Details