Skip to main content
OpenTrials

Clinical trial discovery

Find Clinical Trials

Search studies by condition, treatment, location, eligibility, or trial identifier.

Showing 1–20 of 413 trials

Active filters

Clinical trials found

Published and searchable clinical trials

Searching for clinical trials...
Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

NCT07082725

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +20 more
Locations
  • UCSF Children's Hospital and Research Center at Oakland Oakland, California, United States
  • University of Minnesota Medical School Minneapolis, Minnesota, United States
  • Mayo Clinic Children's Center - PIN Rochester, Minnesota, United States
  • Children's Medical Center Dallas Dallas, Texas, United States
View all 34 locations
View Trial Details
Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

NCT07054515

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +25 more
Locations
  • UCSF Children's Hospital and Research Center at Oakland Oakland, California, United States
  • University of Minnesota Medical School Minneapolis, Minnesota, United States
  • Mayo Clinic Childrens Center - PIN Rochester, Minnesota, United States
  • Children's Medical Center Dallas Dallas, Texas, United States
View all 38 locations
View Trial Details
Recruiting

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

NCT05828069

Conditions
Hemic and Lymphatic Diseases, Histiocytosis, Histiocytosis, Langerhans-Cell, +6 more
Locations
  • Children's Hospital of Alabama Birmingham, Alabama, United States
  • Arkansas Children's Hospital Little Rock, Arkansas, United States
  • Kaiser Permanente Downey Medical Center Downey, California, United States
  • Loma Linda University Medical Center Loma Linda, California, United States
View all 119 locations
View Trial Details
Recruiting

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

NCT07121946

Conditions
DLBCL - Diffuse Large B Cell Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Follicular Lymphoma ( FL), +18 more
Locations
  • City of Hope Duarte, California, United States
  • Washington University School of Medicine St Louis, Missouri, United States
  • Roswell Park Cancer Institute Buffalo, New York, United States
  • Memorial Sloan Kettering Cancer Center - Bergen New York, United States
View Trial Details
Recruiting

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

NCT06160791

Conditions
Hemic and Lymphatic Diseases, Hemophagocytic Lymphohistiocytoses, Histiocytosis, +3 more
Locations
  • University of California, Irvine Irvine, California, United States
  • University of California Davis Comprehensive Cancer Center Sacramento, California, United States
  • University of California, San Diego San Diego, California, United States
  • University of California, San Francisco San Francisco, California, United States
View Trial Details
Recruiting

A Study to Evaluate the Safety and Efficacy of Nizubaglustat (AZ-3102) in Patients With GM2 Gangliosidosis or Niemann-Pick Type C Disease

NCT07399704

Conditions
Brain Diseases, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, +23 more
Locations
  • Associação Hospitalar de Prot à Infância Dr. Raul Carneiro Água Verde, Curitiba, Brazil
  • Hospital de Clinicas de Porto Alegre Porto Alegre, Rio Grande do Sul, Brazil
  • Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira Rio de Janeiro, Brazil
View Trial Details
Recruiting

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

NCT05786924

Conditions
Acquired Resistance to KRAS G12C Inhibitor, BRAF, BRAF Gene Mutation, +61 more
Locations
  • Banner Health- MD Anderson Cancer Center Gilbert, Arizona, United States
  • The Angeles clinic - A cedars SINAI AFFILIATE Los Angeles, California, United States
  • USC Norris Comprehensive Cancer Center Los Angeles, California, United States
  • University of California, San Francisco (UCSF) San Francisco, California, United States
View all 27 locations
View Trial Details
Recruiting

Dose Determining Study of EXS73565 in Participants With Relapsed or Refractory B-Cell Malignancies

NCT06980116

Conditions
Blood Protein Disorders, Cardiovascular Diseases, Chronic Disease, +38 more
Locations
  • LLC ARENSIA Exploratory Medicine Tbilisi, Georgia
  • IMSP Institute of Oncology, ARENSIA Exploratory Medicine Chisinau, Moldova
  • Hospital Beata Maria Ana Madrid, Spain
  • Hospital Fundación Jiménez Diaz Madrid, Spain
View Trial Details
Recruiting

CAR-T Followed by Bispecific Antibodies

NCT04889716

Conditions
DLBCL - Diffuse Large B Cell Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Hemic and Lymphatic Diseases, +6 more
Locations
  • University of Nebraska Medical Center Omaha, Nebraska, United States
  • Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States
View Trial Details
Recruiting

SynKIR-310 for Relapsed/Refractory B-NHL

NCT06544265

Conditions
Aggressive B-Cell Non-Hodgkin Lymphoma, B Cell Lymphoma, Blood Protein Disorders, +54 more
Locations
  • Colorado Blood Cancer Institute, part of Sarah Cannon Cancer Institute Denver, Colorado, United States
  • Winship Cancer Institute of Emory University Atlanta, Georgia, United States
  • The University of Kansas Cancer Center Fairway, Kansas, United States
  • Rutgers Cancer Institute New Brunswick, New Jersey, United States
View Trial Details